产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF7832, RRID:AB_2841273.
展开/折叠
antigen MSK39 identified by monoclonal antibody 5.1H11; antigen recognized by monoclonal antibody 5.1H11; CD56; cell adhesion molecule, neural, 1; MSK 39; MSK39; N-CAM-1; NCAM 1; NCAM; NCAM C; NCAM-1; NCAM1; NCAM1_HUMAN; NCAMC; Neural cell adhesion molecule 1; Neural cell adhesion molecule NCAM; OTTHUMP00000235666;
抗原和靶标
- P13591 NCAM1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLQTKDLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRALSSEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTSGLSTGAIVGILIVIFVLLLVVVDITCYFLNKCGLFMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEKGPVEAKPECQETETKPAPAEVKTVPNDATQTKENESKA
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P13591 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T125 | O-Glycosylation | Uniprot | |
| R130 | Methylation | Uniprot | |
| T328 | Phosphorylation | Uniprot | |
| S398 | Phosphorylation | Uniprot | |
| N459 | N-Glycosylation | Uniprot | |
| S566 | Phosphorylation | Uniprot | |
| T605 | Phosphorylation | Uniprot | |
| S613 | Phosphorylation | Uniprot | |
| Y744 | Phosphorylation | Uniprot | |
| K776 | Ubiquitination | Uniprot | |
| S780 | Phosphorylation | Uniprot | |
| S784 | Phosphorylation | Uniprot | |
| K785 | Ubiquitination | Uniprot | |
| C829 | S-Nitrosylation | Uniprot | |
| T849 | Phosphorylation | Uniprot | |
| K852 | Ubiquitination | Uniprot |
研究背景
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
(Microbial infection) Acts as a receptor for rabies virus.
Cell membrane>Single-pass type I membrane protein.
Cell membrane>Single-pass type I membrane protein.
Cell membrane>Lipid-anchor.
Cell membrane>Lipid-anchor.
Secreted.
Secreted.
(Microbial infection) Interacts with rabies virus glycoprotein.
Interacts with MDK.
研究领域
· Environmental Information Processing > Signaling molecules and interaction > Cell adhesion molecules (CAMs). (View pathway)
· Human Diseases > Neurodegenerative diseases > Prion diseases.
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