产品: MNX1 抗体
货号: DF7864
描述: Rabbit polyclonal antibody to MNX1
应用: WB IF/ICC
反应: Human, Mouse, Rat
预测: Zebrafish, Bovine, Dog
分子量: 41 kDa; 41kD(Calculated).
蛋白号: P50219
RRID: AB_2841295

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 50ul RMB¥ 1250 现货
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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Zebrafish(86%), Bovine(82%), Dog(91%)
克隆:
Polyclonal
特异性:
MNX1 Antibody detects endogenous levels of total MNX1.
RRID:
AB_2841295
引用格式: Affinity Biosciences Cat# DF7864, RRID:AB_2841295.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

HB 9; HB9; HLXB 9; HLXB9; Homeo box HB9; Homeobox HB9; Homeobox protein HB9; HOXHB9; MNX1; MNX1_HUMAN; Motor neuron and pancreas homeobox 1; Motor neuron and pancreas homeobox protein 1; Sacral agenesis autosomal dominant (Currarino triad); SCRA 1; SCRA1;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
P50219 MNX1_HUMAN:

Expressed in lymphoid and pancreatic tissues.

序列:
MEKSKNFRIDALLAVDPPRAASAQSAPLALVTSLAAAASGTGGGGGGGGASGGTSGSCSPASSEPPAAPADRLRAESPSPPRLLAAHCALLPKPGFLGAGGGGGGTGGGHGGPHHHAHPGAAAAAAAAAAAAAAGGLALGLHPGGAQGGAGLPAQAALYGHPVYGYSAAAAAAALAGQHPALSYSYPQVQGAHPAHPADPIKLGAGTFQLDQWLRASTAGMILPKMPDFNSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKEQAAQEAEKQKGGGGGAGKGGAEEPGAEELLGPPAPGDKGSGRRLRDLRDSDPEEDEDEDDEDHFPYSNGASVHAASSDCSSEDDSPPPRPSHQPAPQ

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Dog
91
Zebrafish
86
Bovine
82
Xenopus
57
Chicken
45
Pig
44
Horse
0
Sheep
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P50219 作为底物

Site PTM Type Enzyme
M1 Acetylation
S77 Phosphorylation P49841 (GSK3B)
S79 Phosphorylation P49841 (GSK3B)
R215 Methylation
K225 Ubiquitination
K240 Ubiquitination
K264 Ubiquitination
Y265 Phosphorylation
S267 Phosphorylation
K322 Ubiquitination
K342 Ubiquitination

研究背景

功能:

Putative transcription factor involved in pancreas development and function.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in lymphoid and pancreatic tissues.

研究领域

· Human Diseases > Endocrine and metabolic diseases > Maturity onset diabetes of the young.

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