产品: | Hemoglobin subunit alpha 抗体 |
货号: | DF7893 |
描述: | Rabbit polyclonal antibody to Hemoglobin subunit alpha |
应用: | WB IF/ICC |
反应: | Human |
预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken |
分子量: | 15 kDa, 25 kDa; 15kD(Calculated). |
蛋白号: | P69905 |
RRID: | AB_2841314 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF7893, RRID:AB_2841314.
展开/折叠
Alpha 1 globin; Alpha globin; Alpha one globin; Alpha-globin; HBA_HUMAN; HBA1; HBA2; Hemoglobin alpha 1; Hemoglobin alpha 1 chain; Hemoglobin alpha 1 globin chain; Hemoglobin alpha 2; Hemoglobin alpha chain; Hemoglobin subunit alpha; MGC126895; MGC126897;
抗原和靶标
- P69905 HBA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P69905 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S4 | O-Glycosylation | Uniprot | |
S4 | Phosphorylation | Uniprot | |
K8 | Acetylation | Uniprot | |
T9 | Phosphorylation | Uniprot | |
K12 | Acetylation | Uniprot | |
K17 | Acetylation | Uniprot | |
K17 | Ubiquitination | Uniprot | |
Y25 | Phosphorylation | Uniprot | |
S36 | O-Glycosylation | Uniprot | |
S36 | Phosphorylation | Uniprot | |
T39 | Phosphorylation | Uniprot | |
T40 | Phosphorylation | Uniprot | |
K41 | Acetylation | Uniprot | |
K41 | Ubiquitination | Uniprot | |
T42 | Phosphorylation | Uniprot | |
Y43 | Phosphorylation | Uniprot | |
S50 | Phosphorylation | Uniprot | |
S53 | Phosphorylation | Uniprot | |
K57 | Acetylation | Uniprot | |
K57 | Ubiquitination | Uniprot | |
K61 | Acetylation | Uniprot | |
K61 | Ubiquitination | Uniprot | |
K62 | Acetylation | Uniprot | |
S82 | Phosphorylation | Uniprot | |
K91 | Acetylation | Uniprot | |
K100 | Acetylation | Uniprot | |
C105 | S-Nitrosylation | Uniprot | |
T109 | Phosphorylation | Uniprot | |
S132 | Phosphorylation | Uniprot | |
S134 | O-Glycosylation | Uniprot | |
T135 | Phosphorylation | Uniprot | |
T138 | Phosphorylation | Uniprot | |
S139 | Phosphorylation | Uniprot | |
K140 | Acetylation | Uniprot | |
Y141 | Phosphorylation | Uniprot |
研究背景
Involved in oxygen transport from the lung to the various peripheral tissues.
The initiator Met is not cleaved in variant Thionville and is acetylated.
Red blood cells.
Heterotetramer of two alpha chains and two beta chains in adult hemoglobin A (HbA); two alpha chains and two delta chains in adult hemoglobin A2 (HbA2); two alpha chains and two epsilon chains in early embryonic hemoglobin Gower-2; two alpha chains and two gamma chains in fetal hemoglobin F (HbF).
(Microbial infection) Interacts with Staphylococcus aureus protein isdB.
Belongs to the globin family.
研究领域
· Human Diseases > Infectious diseases: Parasitic > African trypanosomiasis.
· Human Diseases > Infectious diseases: Parasitic > Malaria.
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