| 产品: | FDX1 抗体 |
| 货号: | DF7950 |
| 描述: | Rabbit polyclonal antibody to FDX1 |
| 应用: | WB IF/ICC |
| 反应: | Human |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 19 kDa; 19kD(Calculated). |
| 蛋白号: | P10109 |
| RRID: | AB_2841351 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF7950, RRID:AB_2841351.
展开/折叠
Adrenal ferredoxin; Adrenodoxin; Adrenodoxin, mitochondrial; ADX; ADX_HUMAN; FDX; fdx1; Ferredoxin 1; Ferredoxin-1; Hepatoredoxin; LOH11CR1D; Mitochondrial adrenodoxin; mitochondrial;
抗原和靶标
Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).
- P10109 ADX_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAAGGARLLRAASAVLGGPAGRWLHHAGSRAGSSGLLRNRGPGGSAEASRSLSVSARARSSSEDKITVHFINRDGETLTTKGKVGDSLLDVVVENNLDIDGFGACEGTLACSTCHLIFEDHIYEKLDAITDEENDMLDLAYGLTDRSRLGCQICLTKSMDNMTVRVPETVADARQSIDVGKTS
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P10109 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S35 | Phosphorylation | Uniprot | |
| S46 | Phosphorylation | Uniprot | |
| S56 | Phosphorylation | Uniprot | |
| S61 | Phosphorylation | Uniprot | |
| S63 | Phosphorylation | Uniprot | |
| T68 | Phosphorylation | Uniprot | |
| T131 | Phosphorylation | Uniprot | |
| R149 | Methylation | Uniprot | |
| S159 | Phosphorylation | Uniprot | |
| T170 | Phosphorylation | Uniprot | |
| S177 | Phosphorylation | Uniprot |
研究背景
Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons (By similarity).
Mitochondrion matrix.
Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).
Interacts with CYP11A1.
Belongs to the adrenodoxin/putidaredoxin family.
限制条款
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