产品: | CCR7 抗体 |
货号: | AF0395 |
描述: | Rabbit polyclonal antibody to CCR7 |
应用: | WB IF/ICC |
反应: | Human, Monkey |
分子量: | 43kDa; 43kD(Calculated). |
蛋白号: | P32248 |
RRID: | AB_2834417 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF0395, RRID:AB_2834417.
展开/折叠
BLR 2; BLR2; C C chemokine receptor type 7; C C CKR 7; C-C chemokine receptor type 7; C-C CKR-7; CC chemokine receptor 7; CC chemokine receptor type 7; CC CKR 7; CC-CKR-7; CCCKR7; CCR 7; CCR-7; Ccr7; CCR7_HUMAN; CD 197; CD197; CD197 antigen; CDw197; Chemokine (C C motif) receptor 7; Chemokine (C C) receptor 7; Chemokine C C motif receptor 7; Chemokine C C receptor 7; Chemokine receptor 7; Chemokine receptor 7-like protein; CMKBR7; EBI 1; EBI1; Ebi1h; EBV Induced G Protein Coupled Receptor 1; EBV-induced G-protein coupled receptor 1; Epstein Barr virus induced G protein coupled receptor; Epstein Barr virus induced gene 1; Epstein-Barr virus-induced G-protein coupled receptor 1; EVI 1; EVI1; Lymphocyte Specific G Protein Coupled Peptide Receptor; MGC108519; MIP 3 beta receptor; MIP-3 beta receptor; MIP3 Beta Receptor;
抗原和靶标
Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.
- P32248 CCR7_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDLGKPMKSVLVVALLVIFQVCLCQDEVTDDYIGDNTTVDYTLFESLCSKKDVRNFKAWFLPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKSWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRHIRRSSMSVEAETTTTFSP
翻译修饰 - P32248 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
Y65 | Phosphorylation | Uniprot | |
S66 | Phosphorylation | Uniprot | |
S151 | Phosphorylation | Uniprot | |
Y155 | Phosphorylation | P12931 (SRC) | Uniprot |
K342 | Ubiquitination | Uniprot | |
S356 | Phosphorylation | Uniprot | |
S357 | Phosphorylation | Uniprot | |
S364 | Phosphorylation | Uniprot | |
S365 | Phosphorylation | Uniprot | |
T372 | Phosphorylation | Uniprot | |
T373 | Phosphorylation | Uniprot | |
T374 | Phosphorylation | Uniprot | |
T375 | Phosphorylation | Uniprot | |
S377 | Phosphorylation | Uniprot |
研究背景
Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
Cell membrane>Multi-pass membrane protein.
Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.
Belongs to the G-protein coupled receptor 1 family.
研究领域
· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction. (View pathway)
· Organismal Systems > Immune system > Chemokine signaling pathway. (View pathway)
限制条款
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