| 产品: | BCAM 抗体 |
| 货号: | DF8041 |
| 描述: | Rabbit polyclonal antibody to BCAM |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Dog |
| 分子量: | 85 kDa; 67kD(Calculated). |
| 蛋白号: | P50895 |
| RRID: | AB_2841403 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8041, RRID:AB_2841403.
展开/折叠
Antigen identified by monoclonal antibody F8; AU; Auberger B antigen; B CAM cell surface glycoprotein; B cell adhesion molecule; B-CAM cell surface glycoprotein; Basal cell adhesion molecule (Lu and Au blood groups); Basal cell adhesion molecule (Lutheran blood group); Basal cell adhesion molecule; Basal cell adhesion molecule Lu and Au blood groups; Basal cell adhesion molecule Lutheran blood group; Bcam; BCAM_HUMAN; CD239; CD239 antigen; F8/G253 antigen; Glycoprotein 95kDa; LU; Lutheran; Lutheran antigen; Lutheran blood group (Auberger b antigen included); Lutheran blood group Auberger b antigen included; Lutheran blood group glycoprotein; MSK19;
抗原和靶标
Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.
- P50895 BCAM_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEPPDAPAQARGAPRLLLLAVLLAAHPDAQAEVRLSVPPLVEVMRGKSVILDCTPTGTHDHYMLEWFLTDRSGARPRLASAEMQGSELQVTMHDTRGRSPPYQLDSQGRLVLAEAQVGDERDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLSVMEDSAQEIATCNSRNGNPAPKITWYRNGQRLEVPVEMNPEGYMTSRTVREASGLLSLTSTLYLRLRKDDRDASFHCAAHYSLPEGRHGRLDSPTFHLTLHYPTEHVQFWVGSPSTPAGWVREGDTVQLLCRGDGSPSPEYTLFRLQDEQEEVLNVNLEGNLTLEGVTRGQSGTYGCRVEDYDAADDVQLSKTLELRVAYLDPLELSEGKVLSLPLNSSAVVNCSVHGLPTPALRWTKDSTPLGDGPMLSLSSITFDSNGTYVCEASLPTVPVLSRTQNFTLLVQGSPELKTAEIEPKADGSWREGDEVTLICSARGHPDPKLSWSQLGGSPAEPIPGRQGWVSSSLTLKVTSALSRDGISCEASNPHGNKRHVFHFGTVSPQTSQAGVAVMAVAVSVGLLLLVVAVFYCVRRKGGPCCRQRREKGAPPPGEPGLSHSGSEQPEQTGLLMGGASGGARGGSGGFGDEC
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P50895 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T205 | Phosphorylation | Uniprot | |
| S206 | Phosphorylation | Uniprot | |
| S213 | Phosphorylation | Uniprot | |
| Y223 | Phosphorylation | Uniprot | |
| S296 | Phosphorylation | Uniprot | |
| Y301 | Phosphorylation | Uniprot | |
| T302 | Phosphorylation | Uniprot | |
| Y360 | Phosphorylation | Uniprot | |
| S367 | Phosphorylation | Uniprot | |
| N439 | N-Glycosylation | Uniprot | |
| K458 | Ubiquitination | Uniprot | |
| S486 | Phosphorylation | Uniprot | |
| S541 | Phosphorylation | Uniprot | |
| K585 | Ubiquitination | Uniprot | |
| S596 | Phosphorylation | P49841 (GSK3B) | Uniprot |
| S598 | Phosphorylation | P68400 (CSNK2A1) | Uniprot |
| S600 | Phosphorylation | Uniprot | |
| S614 | Phosphorylation | Uniprot | |
| S621 | Phosphorylation | P17612 (PRKACA) | Uniprot |
| C628 | S-Nitrosylation | Uniprot |
研究背景
Laminin alpha-5 receptor. May mediate intracellular signaling.
Epinephrine-stimulated phosphorylation of Ser-621 by PKA enhances adhesion to laminin.
Membrane>Single-pass type I membrane protein.
Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.
限制条款
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