产品: | HSPA14 抗体 |
货号: | DF8060 |
描述: | Rabbit polyclonal antibody to HSPA14 |
应用: | WB IF/ICC |
反应: | Human, Monkey |
预测: | Pig, Bovine, Horse, Rabbit, Dog |
分子量: | 55 kDa; 55kD(Calculated). |
蛋白号: | Q0VDF9 |
RRID: | AB_2841416 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8060, RRID:AB_2841416.
展开/折叠
Heat shock 70 kDa protein 14; Heat shock 70kDa protein 14; Heat shock protein HSP60; Heat shock protein hsp70 related protein; HSP60; HSP70 4; HSP70 like protein 1; HSP70-like protein 1; HSP70L1; HSP7E_HUMAN; HSPA 14; HSPA14; MGC131990;
抗原和靶标
- Q0VDF9 HSP7E_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNISNTVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGIGQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLASEFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSIPPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGTPLPARRQHTLQAPGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLHVTCTDQETGKCEAISIEIAS
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q0VDF9 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
K53 | Ubiquitination | Uniprot | |
K66 | Ubiquitination | Uniprot | |
K68 | Ubiquitination | Uniprot | |
S75 | Phosphorylation | Uniprot | |
S76 | Phosphorylation | Uniprot | |
K82 | Ubiquitination | Uniprot | |
S87 | Phosphorylation | Uniprot | |
K88 | Ubiquitination | Uniprot | |
Y100 | Phosphorylation | Uniprot | |
K109 | Ubiquitination | Uniprot | |
K123 | Ubiquitination | Uniprot | |
K125 | Ubiquitination | Uniprot | |
K150 | Ubiquitination | Uniprot | |
S186 | Phosphorylation | Uniprot | |
S219 | Phosphorylation | Uniprot | |
K260 | Acetylation | Uniprot | |
Y286 | Phosphorylation | Uniprot | |
S305 | Phosphorylation | Uniprot | |
K310 | Ubiquitination | Uniprot | |
K331 | Ubiquitination | Uniprot | |
K343 | Ubiquitination | Uniprot | |
K402 | Ubiquitination | Uniprot | |
T420 | Phosphorylation | Uniprot | |
T456 | Phosphorylation | Uniprot | |
K457 | Ubiquitination | Uniprot | |
K468 | Ubiquitination | Uniprot | |
K469 | Acetylation | Uniprot | |
T481 | Phosphorylation | Uniprot | |
S487 | Phosphorylation | Uniprot |
研究背景
Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity.
Cytoplasm>Cytosol.
Component of ribosome-associated complex (RAC), a heterodimer composed of Hsp70/DnaK-type chaperone HSPA14 and Hsp40/DnaJ-type chaperone DNAJC2.
Belongs to the heat shock protein 70 family.
限制条款
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