| 产品: | FDFT1 抗体 |
| 货号: | DF8121 |
| 描述: | Rabbit polyclonal antibody to FDFT1 |
| 应用: | WB IHC |
| 反应: | Human |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 48 kDa; 48kD(Calculated). |
| 蛋白号: | P37268 |
| RRID: | AB_2841461 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8121, RRID:AB_2841461.
展开/折叠
DGPT; ERG9; Farnesyl diphosphate farnesyltransferase; Farnesyl-diphosphate farnesyltransferase; FDFT_HUMAN; FDFT1; FPP:FPP farnesyltransferase; SQS; Squalene synthase; Squalene synthetase; SS;
抗原和靶标
- P37268 FDFT_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P37268 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K5 | Ubiquitination | Uniprot | |
| C6 | S-Nitrosylation | Uniprot | |
| Y14 | Phosphorylation | Uniprot | |
| K30 | Ubiquitination | Uniprot | |
| K41 | Ubiquitination | Uniprot | |
| K45 | Ubiquitination | Uniprot | |
| K92 | Ubiquitination | Uniprot | |
| K93 | Ubiquitination | Uniprot | |
| K115 | Ubiquitination | Uniprot | |
| K117 | Ubiquitination | Uniprot | |
| T127 | Phosphorylation | Uniprot | |
| S129 | Phosphorylation | Uniprot | |
| K138 | Ubiquitination | Uniprot | |
| K160 | Ubiquitination | Uniprot | |
| S164 | Phosphorylation | Uniprot | |
| K213 | Ubiquitination | Uniprot | |
| K318 | Ubiquitination | Uniprot | |
| Y346 | Phosphorylation | Uniprot | |
| S352 | Phosphorylation | Uniprot | |
| K358 | Ubiquitination | Uniprot |
研究背景
Endoplasmic reticulum membrane>Multi-pass membrane protein.
Widely expressed.
Monomer.
Belongs to the phytoene/squalene synthase family.
研究领域
· Metabolism > Lipid metabolism > Steroid biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
限制条款
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