| 产品: | PTS 抗体 |
| 货号: | DF8130 |
| 描述: | Rabbit polyclonal antibody to PTS |
| 应用: | WB IF/ICC |
| 反应: | Human |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken |
| 分子量: | 16 kDa; 16kD(Calculated). |
| 蛋白号: | Q03393 |
| RRID: | AB_2841466 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8130, RRID:AB_2841466.
展开/折叠
6 pyruvoyl tetrahydrobiopterin synthase; 6 pyruvoyl tetrahydropterin synthase; 6 pyruvoyltetrahydropterin synthase; 6-pyruvoyl tetrahydrobiopterin synthase; EC 4.2.3.12; FLJ97081; OTTHUMP00000235385; PTP synthase; PTPS; PTPS_HUMAN; PTS;
抗原和靶标
- Q03393 PTPS_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSTEGGGRRCQAQVSRRISFSASHRLYSKFLSDEENLKLFGKCNNPNGHGHNYKVVVTVHGEIDPATGMVMNLADLKKYMEEAIMQPLDHKNLDMDVPYFADVVSTTENVAVYIWDNLQKVLPVGVLYKVKVYETDNNIVVYKGE
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q03393 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S19 | Phosphorylation | Q13976 (PRKG1) , Q13237 (PRKG2) | Uniprot |
| S21 | Phosphorylation | Uniprot | |
| S23 | Phosphorylation | Uniprot | |
| K29 | Ubiquitination | Uniprot | |
| S32 | Phosphorylation | Uniprot | |
| K38 | Ubiquitination | Uniprot | |
| K42 | Ubiquitination | Uniprot | |
| K77 | Ubiquitination | Uniprot | |
| Y128 | Phosphorylation | Uniprot | |
| K129 | Ubiquitination | Uniprot | |
| K131 | Ubiquitination | Uniprot | |
| K143 | Ubiquitination | Uniprot |
研究背景
Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.
Phosphorylation of Ser-19 is required for maximal enzyme activity.
Homohexamer formed of two homotrimers in a head to head fashion.
Belongs to the PTPS family.
研究领域
· Metabolism > Metabolism of cofactors and vitamins > Folate biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
限制条款
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