| 产品: | TAF9B 抗体 |
| 货号: | DF8206 |
| 描述: | Rabbit polyclonal antibody to TAF9B |
| 应用: | WB |
| 反应: | Human, Mouse |
| 预测: | Bovine, Horse, Sheep, Dog |
| 分子量: | 28 kDa; 28kD(Calculated). |
| 蛋白号: | Q9HBM6 |
| RRID: | AB_2841514 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8206, RRID:AB_2841514.
展开/折叠
DN-7; DN7; Neuronal cell death related protein 7; Neuronal cell death-related protein 7; TAF9-like RNA polymerase II TBP associated factor, 31 kD; Taf9b; TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa; TAF9B_HUMAN; TAF9L; TAFII31L; TFIID-31; Transcription initiation factor TFIID subunit 9-like; Transcription initiation factor TFIID subunit 9-like protein; Transcription initiation factor TFIID subunit 9B; Transcription-associated factor TAFII31L;
抗原和靶标
- Q9HBM6 TAF9B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPNVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLIKKGPNQGRLVPRLSVGAVSSKPTTPTIATPQTVSVPNKVATPMSVTSQRFTVQIPPSQSTPVKPVPATTAVQNVLINPSMIGPKNILITTNMVSSQNTANEANPLKRKHEDDDDNDIM
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9HBM6 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| S3 | Phosphorylation | Uniprot | |
| K5 | Ubiquitination | Uniprot | |
| K10 | Ubiquitination | Uniprot | |
| K24 | Ubiquitination | Uniprot | |
| Y46 | Phosphorylation | Uniprot | |
| K55 | Ubiquitination | Uniprot | |
| Y57 | Phosphorylation | Uniprot | |
| K62 | Ubiquitination | Uniprot | |
| S82 | Phosphorylation | Uniprot | |
| S85 | Phosphorylation | Uniprot | |
| K99 | Ubiquitination | Uniprot | |
| T102 | Phosphorylation | Uniprot | |
| K108 | Acetylation | Uniprot | |
| K108 | Ubiquitination | Uniprot | |
| R119 | Methylation | Uniprot | |
| R128 | Methylation | Uniprot | |
| S147 | Phosphorylation | Uniprot | |
| S152 | Phosphorylation | Uniprot | |
| S153 | Phosphorylation | Uniprot | |
| T156 | Phosphorylation | Uniprot | |
| T157 | Phosphorylation | Uniprot | |
| T159 | Phosphorylation | Uniprot | |
| T162 | Phosphorylation | Uniprot | |
| T174 | Phosphorylation | Uniprot | |
| S177 | Phosphorylation | Uniprot | |
| S190 | Phosphorylation | Uniprot | |
| S192 | Phosphorylation | Uniprot | |
| T193 | Phosphorylation | Uniprot |
研究背景
Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription.
Nucleus.
Binds TAF5 and TAF6. Component of TFIID and the TATA-binding protein-free TAF complex (TFTC). TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). Binds N-terminal domain of p53/TP53 which is essential for transcription.
Belongs to the TAF9 family.
研究领域
· Genetic Information Processing > Transcription > Basal transcription factors.
· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.
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