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产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8227, RRID:AB_2841527.
展开/折叠
Benzodiazapine receptor (peripheral); Benzodiazepine peripheral binding site; BPBS; BZRP; DBI; IBP; Isoquinoline carboxamide-binding protein; MBR; mDRC; Mitochondrial benzodiazepine receptor; PBR; PBS; Peripheral benzodiazepine receptor; Peripheral benzodiazepine receptor-related protein; Peripheral type benzodiazepine receptor; Peripheral-type benzodiazepine receptor; pk18; PKBS; PTBR; Ptbzr; PTBZR02; RATPTBZR02; translocator protein (18kDa); Translocator protein; Tspo; Tspo1; TSPOA_HUMAN;
抗原和靶标
Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids.
- P30536 TSPO_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P30536 作为底物
| Site | PTM Type | Enzyme | Source |
|---|
研究背景
Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides.
Mitochondrion membrane>Multi-pass membrane protein.
Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids.
Interacts with TSPOAP1 (By similarity). May interact with STAR (By similarity). Interacts with MOST-1.
Belongs to the TspO/BZRP family.
研究领域
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
· Human Diseases > Infectious diseases: Viral > HTLV-I infection.
· Organismal Systems > Digestive system > Cholesterol metabolism.
文献引用
Application: IHC Species: Rat Sample: hippocampus
限制条款
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