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| 产品: | CTSS 抗体 |
| 货号: | DF8246 |
| 描述: | Rabbit polyclonal antibody to CTSS |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 37 kDa; 37kD(Calculated). |
| 蛋白号: | P25774 |
| RRID: | AB_2841541 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8246, RRID:AB_2841541.
展开/折叠
Cathepsin S; CathepsinS; CATS_HUMAN; Ctss;
抗原和靶标
- P25774 CATS_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P25774 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K42 | Ubiquitination | Uniprot | |
| S171 | Phosphorylation | Uniprot | |
| Y175 | Phosphorylation | Uniprot | |
| S200 | Phosphorylation | Uniprot | |
| Y215 | Phosphorylation | Uniprot | |
| S217 | Phosphorylation | Uniprot | |
| Y232 | Phosphorylation | Uniprot | |
| Y262 | Phosphorylation | Uniprot |
研究背景
Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L.
Lysosome. Secreted.
Monomer.
Belongs to the peptidase C1 family.
研究领域
· Cellular Processes > Transport and catabolism > Lysosome. (View pathway)
· Cellular Processes > Transport and catabolism > Phagosome. (View pathway)
· Cellular Processes > Cell growth and death > Apoptosis. (View pathway)
· Human Diseases > Infectious diseases: Bacterial > Tuberculosis.
· Organismal Systems > Immune system > Antigen processing and presentation. (View pathway)
文献引用
Application: WB Species: Mouse Sample:
限制条款
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