| 产品: | MPP1 抗体 |
| 货号: | DF8276 |
| 描述: | Rabbit polyclonal antibody to MPP1 |
| 应用: | WB IF/ICC |
| 反应: | Human |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 52 kDa; 52kD(Calculated). |
| 蛋白号: | Q00013 |
| RRID: | AB_2841565 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8276, RRID:AB_2841565.
展开/折叠
55 kDa erythrocyte membrane protein; AAG 12; AAG12; Aging associated gene 12; DXS552; DXS552E; EM55_HUMAN; EMP 55; EMP55; Erythrocyte membrane protein p55; Membrane protein; Membrane protein palmitoylated 1 55kDa; Membrane protein palmitoylated 1; Membrane protein, palmitoylated 1, 55kDa; Migration related gene 1; MPP 1; MPP1; MRG 1; MRG1; OTTHUMP00000026054; OTTHUMP00000196176; p55; palmitoylated 1; Palmitoylated erythrocyte membrane protein; Palmitoylated membrane protein 1; PEMP;
抗原和靶标
- Q00013 EM55_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTLKASEGESGGSMHTALSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQVKGQEVRKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEINGTNVTNHSVDQLQKAMKETKGMISLKVIPNQQSRLPALQMFMRAQFDYDPKKDNLIPCKEAGLKFATGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVASMAQSAPSEAPSCSPFGKKKKYKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKNALLSQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFGTKFETVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQGTQTEALQQLQKDSEAIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q00013 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T2 | Acetylation | Uniprot | |
| S13 | Phosphorylation | Uniprot | |
| S19 | Phosphorylation | Uniprot | |
| Y22 | Phosphorylation | Uniprot | |
| K29 | Ubiquitination | Uniprot | |
| S37 | Phosphorylation | Uniprot | |
| T42 | Phosphorylation | Uniprot | |
| T44 | Phosphorylation | Uniprot | |
| Y48 | Phosphorylation | Uniprot | |
| T49 | Phosphorylation | Uniprot | |
| S52 | Phosphorylation | Uniprot | |
| S57 | Phosphorylation | Uniprot | |
| K76 | Ubiquitination | Uniprot | |
| K91 | Ubiquitination | Uniprot | |
| S110 | Phosphorylation | Uniprot | |
| K147 | Ubiquitination | Uniprot | |
| S154 | Phosphorylation | Uniprot | |
| K180 | Ubiquitination | Uniprot | |
| K197 | Ubiquitination | Uniprot | |
| K212 | Acetylation | Uniprot | |
| K212 | Ubiquitination | Uniprot | |
| S220 | Phosphorylation | Uniprot | |
| S241 | Phosphorylation | Uniprot | |
| S243 | Phosphorylation | Uniprot | |
| K247 | Ubiquitination | Uniprot | |
| Y251 | Phosphorylation | Uniprot | |
| Y255 | Phosphorylation | Uniprot | |
| K258 | Ubiquitination | Uniprot | |
| K281 | Methylation | Uniprot | |
| K299 | Ubiquitination | Uniprot | |
| K309 | Ubiquitination | Uniprot | |
| Y316 | Phosphorylation | Uniprot | |
| K323 | Ubiquitination | Uniprot | |
| S324 | Phosphorylation | Uniprot | |
| Y331 | Phosphorylation | Uniprot | |
| S335 | Phosphorylation | Uniprot | |
| S344 | Phosphorylation | Uniprot | |
| K371 | Ubiquitination | Uniprot | |
| K374 | Ubiquitination | Uniprot | |
| K386 | Ubiquitination | Uniprot | |
| T407 | Phosphorylation | Uniprot | |
| K417 | Ubiquitination | Uniprot | |
| Y429 | Phosphorylation | Uniprot |
研究背景
Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity).
Palmitoylated.
Cell membrane>Lipid-anchor. Cell projection>Stereocilium.
Note: Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity). Colocalizes with MPP5 in the retina, at the outer limiting membrane (OLM) (By similarity). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC) (By similarity). Colocalizes with NF2 in non-myelin-forming Schwann cells (PubMed:19144871).
Ubiquitous.
Heterodimer with MPP5. Interacts with DLG5 and NF2. Interacts (via guanylate kinase-like domain) with WHRN (via third PDZ domain).
Belongs to the MAGUK family.
限制条款
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