产品: | KRT12 抗体 |
货号: | DF8321 |
描述: | Rabbit polyclonal antibody to KRT12 |
应用: | WB |
反应: | Human, Mouse |
预测: | Pig, Bovine, Sheep, Rabbit, Dog |
分子量: | 54 kDa; 54kD(Calculated). |
蛋白号: | Q99456 |
RRID: | AB_2841597 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8321, RRID:AB_2841597.
展开/折叠
CK-12; Cytokeratin-12; K12; K1C12_HUMAN; Keratin 12; Keratin; Keratin, type I cytoskeletal 12; Keratin-12; KRT12; type I cytoskeletal 12;
抗原和靶标
- Q99456 K1C12_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDLSNNTMSLSVRTPGLSRRLSSQSVIGRPRGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQSTDSSKDPTKTRKIKTVVQEMVNGEVVSSQVQEIEELM
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q99456 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S22 | Phosphorylation | Uniprot | |
S138 | Phosphorylation | Uniprot | |
Y139 | Phosphorylation | Uniprot | |
K142 | Acetylation | Uniprot | |
K142 | Ubiquitination | Uniprot | |
Y161 | Phosphorylation | Uniprot | |
T163 | Phosphorylation | Uniprot | |
K189 | Ubiquitination | Uniprot | |
Y262 | Phosphorylation | Uniprot | |
S343 | Phosphorylation | Uniprot | |
Y429 | Phosphorylation | Uniprot |
研究背景
May play a unique role in maintaining the normal corneal epithelial function. Together with KRT3, essential for the maintenance of corneal epithelium integrity (By similarity).
Cornea specific.
Heterotetramer of two type I and two type II keratins. Keratin-3 associates with keratin-12.
Belongs to the intermediate filament family.
研究领域
· Organismal Systems > Endocrine system > Estrogen signaling pathway. (View pathway)
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