产品: PCYOX1 抗体
货号: DF8332
描述: Rabbit polyclonal antibody to PCYOX1
应用: WB
反应: Human, Mouse, Rat
分子量: 57 kDa; 57kD(Calculated).
蛋白号: Q9UHG3
RRID: AB_2841603

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
克隆:
Polyclonal
特异性:
PCYOX1 Antibody detects endogenous levels of total PCYOX1.
RRID:
AB_2841603
引用格式: Affinity Biosciences Cat# DF8332, RRID:AB_2841603.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

EC 1.8.3.5; KIAA0908; PCL1; PCYOX_HUMAN; PCYOX1; Prenylcysteine lyase; Prenylcysteine oxidase 1; Prenylcysteine oxidase precursor;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
Q9UHG3 PCYOX_HUMAN:

Ubiquitous.

序列:
MGRVVAELVSSLLGLWLLLCSCGCPEGAELRAPPDKIAIIGAGIGGTSAAYYLRQKFGKDVKIDLFEREEVGGRLATMMVQGQEYEAGGSVIHPLNLHMKRFVKDLGLSAVQASGGLLGIYNGETLVFEESNWFIINVIKLVWRYGFQSLRMHMWVEDVLDKFMRIYRYQSHDYAFSSVEKLLHALGGDDFLGMLNRTLLETLQKAGFSEKFLNEMIAPVMRVNYGQSTDINAFVGAVSLSCSDSGLWAVEGGNKLVCSGLLQASKSNLISGSVMYIEEKTKTKYTGNPTKMYEVVYQIGTETRSDFYDIVLVATPLNRKMSNITFLNFDPPIEEFHQYYQHIVTTLVKGELNTSIFSSRPIDKFGLNTVLTTDNSDLFINSIGIVPSVREKEDPEPSTDGTYVWKIFSQETLTKAQILKLFLSYDYAVKKPWLAYPHYKPPEKCPSIILHDRLYYLNGIECAASAMEMSAIAAHNAALLAYHRWNGHTDMIDQDGLYEKLKTEL

翻译修饰 - Q9UHG3 作为底物

Site PTM Type Enzyme
T47 Phosphorylation
Y51 Phosphorylation
K62 Ubiquitination
K162 Ubiquitination
S171 Phosphorylation
Y174 Phosphorylation
S177 Phosphorylation
N196 N-Glycosylation
T202 Phosphorylation
K205 Ubiquitination
C258 S-Nitrosylation
Y308 Phosphorylation
N323 N-Glycosylation
Y339 Phosphorylation
N353 N-Glycosylation
K392 Ubiquitination
Y403 Phosphorylation
K415 Acetylation
K415 Ubiquitination
Y425 Phosphorylation
Y427 Phosphorylation
Y482 Phosphorylation
Y498 Phosphorylation

研究背景

功能:

Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine.

翻译修饰:

The protein is glycosylated at one or more potential N-glycosylation sites.

细胞定位:

Lysosome.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitous.

蛋白家族:

Belongs to the prenylcysteine oxidase family.

研究领域

· Metabolism > Metabolism of terpenoids and polyketides > Terpenoid backbone biosynthesis.

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