| 产品: | FCAR 抗体 |
| 货号: | DF8356 |
| 描述: | Rabbit polyclonal antibody to FCAR |
| 应用: | WB |
| 反应: | Human |
| 分子量: | 60 kDa; 32kD(Calculated). |
| 蛋白号: | P24071 |
| RRID: | AB_2841621 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8356, RRID:AB_2841621.
展开/折叠
CD89; Fc alpha receptor; Fc fragment of IgA, receptor for; FCAR; FCAR_HUMAN; IgA Fc receptor; Immunoglobulin alpha Fc receptor;
抗原和靶标
Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.
- P24071 FCAR_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTDSIHQDYTTQNLIRMAVAGLVLVALLAILVENWHSHTALNKEASADVAEPSWSQQMCQPGLTFARTPSVCK
翻译修饰 - P24071 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y56 | Phosphorylation | Uniprot | |
| N141 | N-Glycosylation | Uniprot | |
| N177 | N-Glycosylation | Uniprot |
研究背景
Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.
Cell membrane>Single-pass type I membrane protein.
Cell membrane>Single-pass type I membrane protein.
Cell membrane>Single-pass type I membrane protein.
Secreted.
Secreted.
Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.
Associates with the Fc epsilon RI gamma 2 receptor inducing tyrosine phosphorylation of gamma 2.
(Microbial infection) Interacts with Staphylococcus aureus protein SSL11.
研究领域
· Cellular Processes > Transport and catabolism > Phagosome. (View pathway)
· Human Diseases > Infectious diseases: Bacterial > Staphylococcus aureus infection.
限制条款
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