| 产品: | ALOX5AP 抗体 |
| 货号: | DF8367 |
| 描述: | Rabbit polyclonal antibody to ALOX5AP |
| 应用: | WB |
| 反应: | Human, Rat |
| 预测: | Pig, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 18 kDa; 18kD(Calculated). |
| 蛋白号: | P20292 |
| RRID: | AB_2841631 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8367, RRID:AB_2841631.
展开/折叠
5-lipoxygenase activating protein; AL5AP_HUMAN; ALOX 5AP; ALOX5 AP; ALOX5AP; Arachidonate 5 lipoxygenase activating protein; Arachidonate 5-lipoxygenase-activating protein; Five lipoxygenase activating protein; FLAP; MK 886 binding protein; MK-886-binding protein;
抗原和靶标
- P20292 AL5AP_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNCVDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P20292 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S41 | Phosphorylation | Uniprot |
研究背景
Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.
Nucleus membrane>Multi-pass membrane protein. Endoplasmic reticulum membrane>Multi-pass membrane protein.
Homotrimer. Interacts with LTC4S and ALOX5.
The C-terminal part after residue 140 is mostly unstructured.
Belongs to the MAPEG family.
研究领域
· Organismal Systems > Immune system > Fc epsilon RI signaling pathway. (View pathway)
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