| 产品: | SSB 抗体 |
| 货号: | DF8417 |
| 描述: | Rabbit polyclonal antibody to SSB |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse |
| 预测: | Pig, Bovine, Horse, Sheep, Dog |
| 分子量: | 46 kDa; 47kD(Calculated). |
| 蛋白号: | P05455 |
| RRID: | AB_2841666 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8417, RRID:AB_2841666.
展开/折叠
Autoantigen La; La; La autoantigen; La autoantigen homolog; La protein; La ribonucleoprotein; La ribonucleoprotein domain family member 3; LA_HUMAN; LARP3; Lupus La antigen; Lupus La protein; Lupus La protein homolog; MGC118101; MGC93380; mRNA for autoantigen; OTTMUSP00000014043; RP23 273G23.1; Sjoegren syndrome type B antigen; Sjogren syndrome antigen B (autoantigen La); Sjogren syndrome antigen B; SS B; SS-B; SS-B/La protein; SSB;
抗原和靶标
- P05455 LA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P05455 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K9 | Ubiquitination | Uniprot | |
| Y23 | Phosphorylation | Uniprot | |
| Y24 | Phosphorylation | Uniprot | |
| K37 | Ubiquitination | Uniprot | |
| K41 | Sumoylation | Uniprot | |
| K41 | Ubiquitination | Uniprot | |
| K74 | Ubiquitination | Uniprot | |
| K76 | Ubiquitination | Uniprot | |
| S83 | Phosphorylation | Uniprot | |
| K86 | Sumoylation | Uniprot | |
| K86 | Ubiquitination | Uniprot | |
| S92 | Phosphorylation | Uniprot | |
| S94 | Phosphorylation | Uniprot | |
| K95 | Acetylation | Uniprot | |
| K95 | Ubiquitination | Uniprot | |
| Y104 | Phosphorylation | Uniprot | |
| K105 | Ubiquitination | Uniprot | |
| K116 | Acetylation | Uniprot | |
| K116 | Ubiquitination | Uniprot | |
| T120 | Phosphorylation | Uniprot | |
| K128 | Acetylation | Uniprot | |
| K128 | Ubiquitination | Uniprot | |
| K165 | Acetylation | Uniprot | |
| K166 | Ubiquitination | Uniprot | |
| K174 | Ubiquitination | Uniprot | |
| K176 | Ubiquitination | Uniprot | |
| T178 | Phosphorylation | Uniprot | |
| K185 | Acetylation | Uniprot | |
| K185 | Sumoylation | Uniprot | |
| Y188 | Phosphorylation | Uniprot | |
| K191 | Methylation | Uniprot | |
| K200 | Sumoylation | Uniprot | |
| K208 | Sumoylation | Uniprot | |
| K208 | Ubiquitination | Uniprot | |
| K216 | Acetylation | Uniprot | |
| K216 | Ubiquitination | Uniprot | |
| K224 | Ubiquitination | Uniprot | |
| S225 | Phosphorylation | Uniprot | |
| K229 | Ubiquitination | Uniprot | |
| C232 | S-Nitrosylation | Uniprot | |
| K235 | Ubiquitination | Uniprot | |
| R266 | Methylation | Uniprot | |
| K269 | Ubiquitination | Uniprot | |
| K276 | Ubiquitination | Uniprot | |
| K280 | Acetylation | Uniprot | |
| K285 | Acetylation | Uniprot | |
| K287 | Ubiquitination | Uniprot | |
| K299 | Ubiquitination | Uniprot | |
| T302 | Phosphorylation | P31749 (AKT1) | Uniprot |
| K312 | Ubiquitination | Uniprot | |
| S325 | Phosphorylation | Uniprot | |
| K328 | Acetylation | Uniprot | |
| K328 | Ubiquitination | Uniprot | |
| K352 | Acetylation | Uniprot | |
| K352 | Ubiquitination | Uniprot | |
| K354 | Acetylation | Uniprot | |
| K354 | Ubiquitination | Uniprot | |
| K360 | Acetylation | Uniprot | |
| K361 | Acetylation | Uniprot | |
| T362 | Phosphorylation | Uniprot | |
| S366 | Phosphorylation | P68400 (CSNK2A1) | Uniprot |
| T379 | Phosphorylation | Uniprot | |
| T389 | Phosphorylation | Uniprot | |
| K391 | Acetylation | Uniprot | |
| K397 | Ubiquitination | Uniprot |
研究背景
Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation. In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation.
Phosphorylated. The phosphorylation sites are at the C-terminal part of the protein.
The N-terminus is blocked.
Nucleus.
Interacts with DDX15. May interact with RUFY1.
研究领域
· Human Diseases > Immune diseases > Systemic lupus erythematosus.
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