| 产品: | WNT5B 抗体 |
| 货号: | DF8438 |
| 描述: | Rabbit polyclonal antibody to WNT5B |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat, Monkey |
| 预测: | Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 40 kDa; 40kD(Calculated). |
| 蛋白号: | Q9H1J7 |
| RRID: | AB_2841684 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8438, RRID:AB_2841684.
展开/折叠
MGC2648; Protein Wnt-5b; Wingless type MMTV integration site family, member 5B; WNT 5B; WNT 5B protein; Wnt family member 5B; Wnt5b; WNT5B protein; WNT5B_HUMAN;
抗原和靶标
- Q9H1J7 WNT5B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPSLLLLFTAALLSSWAQLLTDANSWWSLALNPVQRPEMFIIGAQPVCSQLPGLSPGQRKLCQLYQEHMAYIGEGAKTGIKECQHQFRQRRWNCSTADNASVFGRVMQIGSRETAFTHAVSAAGVVNAISRACREGELSTCGCSRTARPKDLPRDWLWGGCGDNVEYGYRFAKEFVDAREREKNFAKGSEEQGRVLMNLQNNEAGRRAVYKMADVACKCHGVSGSCSLKTCWLQLAEFRKVGDRLKEKYDSAAAMRVTRKGRLELVNSRFTQPTPEDLVYVDPSPDYCLRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYNQFKSVQVERCHCKFHWCCFVRCKKCTEIVDQYICK
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9H1J7 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K173 | Ubiquitination | Uniprot | |
| Y210 | Phosphorylation | Uniprot | |
| T230 | Phosphorylation | Uniprot | |
| Y249 | Phosphorylation | Uniprot | |
| S293 | Phosphorylation | Uniprot |
研究背景
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity).
Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
Secreted>Extracellular space>Extracellular matrix.
Interacts with PORCN.
Belongs to the Wnt family.
研究领域
· Cellular Processes > Cellular community - eukaryotes > Signaling pathways regulating pluripotency of stem cells. (View pathway)
· Environmental Information Processing > Signal transduction > mTOR signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Wnt signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Hippo signaling pathway. (View pathway)
· Human Diseases > Infectious diseases: Viral > Human papillomavirus infection.
· Human Diseases > Infectious diseases: Viral > HTLV-I infection.
· Human Diseases > Cancers: Overview > Pathways in cancer. (View pathway)
· Human Diseases > Cancers: Overview > Proteoglycans in cancer.
· Human Diseases > Cancers: Specific types > Basal cell carcinoma. (View pathway)
· Human Diseases > Cancers: Specific types > Breast cancer. (View pathway)
· Human Diseases > Cancers: Specific types > Hepatocellular carcinoma. (View pathway)
· Human Diseases > Cancers: Specific types > Gastric cancer. (View pathway)
· Organismal Systems > Development > Axon guidance. (View pathway)
· Organismal Systems > Endocrine system > Melanogenesis.
限制条款
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