Cathepsin H Antibody - #DF8514

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产品: Cathepsin H 抗体
货号: DF8514
描述: Rabbit polyclonal antibody to Cathepsin H
应用: WB IHC IF/ICC
反应: Human, Mouse
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 37kDa,25kDa; 37kD(Calculated).
蛋白号: P09668
RRID: AB_2841719

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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相关下载
MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
预测:
Pig(88%), Bovine(100%), Horse(88%), Sheep(100%), Rabbit(100%), Dog(88%)
克隆:
Polyclonal
特异性:
Cathepsin H Antibody detects endogenous levels of total Cathepsin H.
RRID:
AB_2841719
引用格式: Affinity Biosciences Cat# DF8514, RRID:AB_2841719.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

ACC 4; ACC 5; ACC4; ACC5; aleurain; CATH_HUMAN; cathepsin B3; cathepsin BA; Cathepsin H heavy chain; Cathepsin H light chain; Cathepsin H mini chain; CPSB; CTSH; minichain; N benzoylarginine beta naphthylamide hydrolase; N-benzoylarginine-beta-naphthylamide hydrolase; pro cathepsin H;

抗原和靶标

免疫原:
Uniprot:

P09668(CATH_HUMAN) >>Visit HPA database.

基因/基因ID:
CTSH(1512)
序列:
MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Bovine
100
Sheep
100
Rabbit
100
Pig
88
Horse
88
Dog
88
Chicken
63
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P09668 作为底物

Site PTM Type Enzyme
Y94 Phosphorylation
N101 N-Glycosylation
S103 Phosphorylation
K106 Ubiquitination
C141 S-Nitrosylation
T204 Phosphorylation
Y205 Phosphorylation
N230 N-Glycosylation

研究背景

功能:

Important for the overall degradation of proteins in lysosomes.

细胞定位:

Lysosome.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Composed of a mini chain and a large chain. The large chain may be split into heavy and light chain. All chains are held together by disulfide bonds.

蛋白家族:

Belongs to the peptidase C1 family.

研究领域

· Cellular Processes > Transport and catabolism > Lysosome.   (View pathway)

· Cellular Processes > Cell growth and death > Apoptosis.   (View pathway)

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