产品: PANK2 抗体
货号: DF8588
描述: Rabbit polyclonal antibody to PANK2
应用: WB IF/ICC
反应: Human
分子量: 62 kDa; 63kD(Calculated).
蛋白号: Q9BZ23
RRID: AB_2841792

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
PANK2 Antibody detects endogenous levels of total PANK2.
RRID:
AB_2841792
引用格式: Affinity Biosciences Cat# DF8588, RRID:AB_2841792.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

4933409I19Rik; AI642621; C20orf48; Hallervorden Spatz syndrome; HARP; hPANK2; HSS; MGC118448; MGC15053; mitochondrial; NBIA1; PANK2; PANK2_HUMAN; Pantothenate kinase 2 (Hallervorden Spatz syndrome); Pantothenate kinase 2; Pantothenate kinase 2 mitochondrial; Pantothenic acid kinase 2; PKAN; RP23 387C21.4;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
Q9BZ23 PANK2_HUMAN:

Ubiquitous.

序列:
MRRLGPFHPRVHWAAPPSLSSGLHRLLFLRGTRIPSSTTLSPPRHDSLSLDGGTVNPPRVREPTGREAFGPSPASSDWLPARWRNGRGGRPRARLCSGWTAAEEARRNPTLGGLLGRQRLLLRMGGGRLGAPMERHGRASATSVSSAGEQAAGDPEGRRQEPLRRRASSASVPAVGASAEGTRRDRLGSYSGPTSVSRQRVESLRKKRPLFPWFGLDIGGTLVKLVYFEPKDITAEEEEEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTLCGRKGNLHFIRFPTHDMPAFIQMGRDKNFSSLHTVFCATGGGAYKFEQDFLTIGDLQLCKLDELDCLIKGILYIDSVGFNGRSQCYYFENPADSEKCQKLPFDLKNPYPLLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFFGLCCLLTGCTTFEEALEMASRGDSTKVDKLVRDIYGGDYERFGLPGWAVASSFGNMMSKEKREAVSKEDLARATLITITNNIGSIARMCALNENINQVVFVGNFLRINTIAMRLLAYALDYWSKGQLKALFSEHEGYFGAVGALLELLKIP

翻译修饰 - Q9BZ23 作为底物

Site PTM Type Enzyme
S140 Phosphorylation
T142 Phosphorylation
S143 Phosphorylation
S168 Phosphorylation
S169 Phosphorylation
S171 Phosphorylation
S189 Phosphorylation
Y190 Phosphorylation
S191 Phosphorylation
T194 Phosphorylation
S195 Phosphorylation
S203 Phosphorylation
K231 Ubiquitination
K246 Ubiquitination
K250 Ubiquitination
K271 Ubiquitination
K279 Ubiquitination
K371 Ubiquitination
S395 Phosphorylation
Y400 Phosphorylation
Y405 Phosphorylation
S470 Phosphorylation
S471 Phosphorylation
S477 Phosphorylation
K486 Ubiquitination
K543 Ubiquitination

研究背景

功能:

May be the master regulator of the CoA biosynthesis.

细胞定位:

Mitochondrion.

Cytoplasm.

Cytoplasm.

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitous.

亚基结构:

Homodimer.

蛋白家族:

Belongs to the type II pantothenate kinase family.

研究领域

· Metabolism > Metabolism of cofactors and vitamins > Pantothenate and CoA biosynthesis.

· Metabolism > Global and overview maps > Metabolic pathways.

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