| 产品: | SEI-1 抗体 |
| 货号: | DF8608 |
| 描述: | Rabbit polyclonal antibody to SEI-1 |
| 应用: | WB |
| 反应: | Human |
| 预测: | Pig, Bovine, Sheep, Rabbit, Dog |
| 分子量: | 24 kDa; 25kD(Calculated). |
| 蛋白号: | Q9UHV2 |
| RRID: | AB_2841812 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8608, RRID:AB_2841812.
展开/折叠
CDK4 binding protein p34SEI; CDK4 binding protein p34SEI1; CDK4-binding protein p34SEI1; SEI-1; SEI1; SERTA domain containing 1; SERTA domain-containing protein 1; SERTAD1; SRTD1_HUMAN; Transcriptional regulator interacting with the PHD-bromodomain 1; TRIP Br1; TRIP-Br1;
抗原和靶标
- Q9UHV2 SRTD1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLSKGLKRKREEEEEKEPLAVDSWWLDPGHTAVAQAPPAVASSSLFDLSVLKLHHSLQQSEPDLRHLVLVVNTLRRIQASMAPAAALPPVPSPPAAPSVADNLLASSDAALSASMASLLEDLSHIEGLSQAPQPLADEGPPGRSIGGAAPSLGALDLLGPATGCLLDDGLEGLFEDIDTSMYDNELWAPASEGLKPGPEDGPGKEEAPELDEAELDYLMDVLVGTQALERPPGPGR
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
Polyubiquitinated, which promotes proteasomal degradation.
Interacts with the PHD-bromodomain of TIF1, TRIM28/TIF1B and p300/CBP. Interacts with E2F1 and TFDP1; modulates transactivation activity of TFDP1/E2F complexes. Also interacts with CDK4.
限制条款
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