| 产品: | UGT8 抗体 |
| 货号: | DF8627 |
| 描述: | Rabbit polyclonal antibody to UGT8 |
| 应用: | WB IF/ICC |
| 反应: | Human, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 61 kDa, 75 kDa; 61kD(Calculated). |
| 蛋白号: | Q16880 |
| RRID: | AB_2841831 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8627, RRID:AB_2841831.
展开/折叠
2 hydroxyacylsphingosine 1 beta galactosyltransferase; 2-hydroxyacylsphingosine 1-beta-galactosyltransferase; Ceramide UDP galactosyltransferase; Ceramide UDP-galactosyltransferase; Cerebroside synthase; CGT; CGT_HUMAN; mCerGT; UDP galactose ceramide galactosyltransferase; UDP galactose ceramide galactosyltransferase 8; UDP glycosyltransferase 8; UDP-galactose-ceramide galactosyltransferase; UGT4; Ugt8; Uridine diphosphate glycosyltransferase 8;
抗原和靶标
- Q16880 CGT_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKSYTPYFILLWSAVGIAKAAKIIIVPPIMFESHMYIFKTLASALHERGHHTVFLLSEGRDIAPSNHYSLQRYPGIFNSTTSDAFLQSKMRNIFSGRLTAIELFDILDHYTKNCDLMVGNHALIQGLKKEKFDLLLVDPNDMCGFVIAHLLGVKYAVFSTGLWYPAEVGAPAPLAYVPEFNSLLTDRMNLLQRMKNTGVYLISRLGVSFLVLPKYERIMQKYNLLPEKSMYDLVHGSSLWMLCTDVALEFPRPTLPNVVYVGGILTKPASPLPEDLQRWVNGANEHGFVLVSFGAGVKYLSEDIANKLAGALGRLPQKVIWRFSGPKPKNLGNNTKLIEWLPQNDLLGHSKIKAFLSHGGLNSIFETIYHGVPVVGIPLFGDHYDTMTRVQAKGMGILLEWKTVTEKELYEALVKVINNPSYRQRAQKLSEIHKDQPGHPVNRTIYWIDYIIRHNGAHHLRAAVHQISFCQYFLLDIAFVLLLGAALLYFLLSWVTKFIYRKIKSLWSRNKHSTVNGHYHNGILNGKYKRNGHIKHEKKVK
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q16880 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K128 | Ubiquitination | Uniprot | |
| Y299 | Phosphorylation | Uniprot | |
| S301 | Phosphorylation | Uniprot | |
| S324 | Phosphorylation | Uniprot | |
| K407 | Ubiquitination | Uniprot | |
| K428 | Ubiquitination | Uniprot | |
| T444 | Phosphorylation | Uniprot | |
| Y519 | Phosphorylation | Uniprot | |
| Y528 | Phosphorylation | Uniprot |
研究背景
Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system.
Membrane>Single-pass membrane protein.
Belongs to the UDP-glycosyltransferase family.
研究领域
· Metabolism > Lipid metabolism > Ether lipid metabolism.
· Metabolism > Lipid metabolism > Sphingolipid metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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