| 产品: | RASSF4 抗体 |
| 货号: | DF8711 |
| 描述: | Rabbit polyclonal antibody to RASSF4 |
| 应用: | WB IF/ICC |
| 反应: | Human, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 36 kDa; 37kD(Calculated). |
| 蛋白号: | Q9H2L5 |
| RRID: | AB_2841915 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8711, RRID:AB_2841915.
展开/折叠
3830411C14Rik; AD037; AI586137; MGC105606; MGC44914; OTTHUMP00000019493; Ras association (RalGDS/AF 6) domain family 4; Ras association (RalGDS/AF 6) domain family member 4; Ras association domain containing protein 4; Ras association domain family 4; Ras association domain-containing protein 4; RASF4_HUMAN; RASSF 4; Rassf4; RP11-285G1.4; Tumor suppressor RASSF4;
抗原和靶标
- Q9H2L5 RASF4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKEDCLPSSHVPISDSKSIQKSELLGLLKTYNCYHEGKSFQLRHREEEGTLIIEGLLNIAWGLRRPIRLQMQDDREQVHLPSTSWMPRRPSCPLKEPSPQNGNITAQGPSIQPVHKAESSTDSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRAPGEAQRIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALYIVHESGERTKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMKFQALRLTMLQRLEQLVEAK
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9H2L5 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K21 | Ubiquitination | Uniprot | |
| S91 | Phosphorylation | Uniprot | |
| S141 | Phosphorylation | Uniprot | |
| S168 | Phosphorylation | Uniprot | |
| K232 | Methylation | Uniprot | |
| S283 | Phosphorylation | Uniprot |
研究背景
Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.
Widely expressed. Frequently down-regulated in tumor cell lines.
Interacts directly with activated KRAS in a GTP-dependent manner.
研究领域
· Environmental Information Processing > Signal transduction > Hippo signaling pathway - multiple species. (View pathway)
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