产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8714, RRID:AB_2841918.
展开/折叠
GTP Rho binding protein 1; GTP-Rho-binding protein 1; ODF5; Outer dense fiber of sperm tails 5; Rhophilin 1; Rhophilin-1; RHPN; Rhpn1; RHPN1_HUMAN;
抗原和靶标
- Q8TCX5 RHPN1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MILEERPDGAGAGEESPRLQGCDSLTQIQCGQLQSRRAQIHQQIDKELQMRTGAENLYRATSNNRVRETVALELSYVNSNLQLLKEELEELSGGVDPGRHGSEAVTVPMIPLGLKETKELDWSTPLKELISVHFGEDGASYEAEIRELEALRQAMRTPSRNESGLELLTAYYNQLCFLDARFLTPARSLGLFFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDRSCTEGARRAMEAFQRAAGAFSLLRENFSHAPSPDMSAASLCALEQLMMAQAQECVFEGLSPPASMAPQDCLAQLRLAQEAAQVAAEYRLVHRTMAQPPVHDYVPVSWTALVHVKAEYFRSLAHYHVAMALCDGSPATEGELPTHEQVFLQPPTSSKPRGPVLPQELEERRQLGKAHLKRAILGQEEALRLHALCRVLREVDLLRAVISQTLQRSLAKYAELDREDDFCEAAEAPDIQPKTHQKPEARMPRLSQGKGPDIFHRLGPLSVFSAKNRWRLVGPVHLTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKAAGEAGASLQVVSLLPSSRLPSLGDRRPVLLGPRGLLRSQREHGCKTPASTWASPRPLLNWSRKAQQGKTGGCPQPCAPVKPAPPSSLKHPGWP
翻译修饰 - Q8TCX5 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S16 | Phosphorylation | Uniprot | |
| S24 | Phosphorylation | Uniprot | |
| T26 | Phosphorylation | Uniprot | |
| S92 | Phosphorylation | Uniprot | |
| K118 | Ubiquitination | Uniprot | |
| T157 | Phosphorylation | Uniprot | |
| S159 | Phosphorylation | Uniprot | |
| S163 | Phosphorylation | Uniprot | |
| S188 | Phosphorylation | Uniprot | |
| K411 | Acetylation | Uniprot | |
| K450 | Ubiquitination | Uniprot | |
| K505 | Ubiquitination | Uniprot | |
| R632 | Methylation | Uniprot |
研究背景
Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules.
Binds specifically to GTP-Rho. Interacts with ROPN1.
The PDZ domain mediates interaction with ROPN1.
Belongs to the RHPN family.
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