| 产品: | LSM1 抗体 |
| 货号: | DF8754 |
| 描述: | Rabbit polyclonal antibody to LSM1 |
| 应用: | WB IHC |
| 反应: | Human, Mouse |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 15~25 kDa; 15kD(Calculated). |
| 蛋白号: | O15116 |
| RRID: | AB_2841958 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8754, RRID:AB_2841958.
展开/折叠
Cancer associated Sm like protein; Cancer associated Sm-like; Cancer-associated Sm-like; CASM; lsm1; LSM1 antibody; LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae); Lsm1 protein; LSM1, U6 small nuclear RNA associated; LSM1_HUMAN; Small nuclear ribonuclear CaSm; U6 snRNA associated Sm-like protein LSm1; U6 snRNA-associated Sm-like protein LSm1; YJL124C;
抗原和靶标
- O15116 LSM1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MNYMPGTASLIEDIDKKHLVLLRDGRTLIGFLRSIDQFANLVLHQTVERIHVGKKYGDIPRGIFVVRGENVVLLGEIDLEKESDTPLQQVSIEEILEEQRVEQQTKLEAEKLKVQALKDRGLSIPRADTLDEY
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O15116 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S123 | Phosphorylation | Uniprot | |
| T129 | Phosphorylation | Uniprot | |
| Y133 | Phosphorylation | Uniprot |
研究背景
Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation (By similarity).
Cytoplasm. Cytoplasm>P-body.
Interacts with SLBP; interaction with SLBP occurs when histone mRNA is being rapidly degraded during the S phase. LSm subunits form a heteromer with a donut shape (By similarity).
Belongs to the snRNP Sm proteins family.
研究领域
· Genetic Information Processing > Folding, sorting and degradation > RNA degradation.
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