产品: | ADRA1D 抗体 |
货号: | DF8793 |
描述: | Rabbit polyclonal antibody to ADRA1D |
应用: | WB IHC |
反应: | Human |
预测: | Pig, Rabbit |
分子量: | 60 kDa; 60kD(Calculated). |
蛋白号: | P25100 |
RRID: | AB_2841991 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8793, RRID:AB_2841991.
展开/折叠
ADA1D_HUMAN; Adra1; Adra1a; Adra1d; ADRA1R; Adrd1; Adrenergic alpha1A receptor; Adrenergic alpha1D receptor; Adrenergic receptor alpha 1d; Adrenergic receptor delta1; Adrenoceptor alpha 1D; Alpha 1D adrenoceptor; Alpha 1D adrenoreceptor; Alpha adrenergic receptor 1a; Alpha-1A adrenergic receptor; Alpha-1D adrenergic receptor; Alpha-1D adrenoceptor; Alpha-1D adrenoreceptor; Alpha-adrenergic receptor 1a; ALPHA1; Alpha1A adrenergic receptor; Alpha1D adrenergic receptor; Alpha1DAR; DAR; dJ779E11.2; Gpcr8; RA42; Spr8;
抗原和靶标
- P25100 ADA1D_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTFRDLLSVSFEGPRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGVVGAGSGEDNRSSAGEPGSAGAGGDVNGTAAVGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVVSVGPLLGWKEPVPPDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADGAHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRRPLWRVYGHHWRASTSGLRQDCAPSSGDAPPGAPLALTALPDPDPEPPGTPEMQAPVASRRKPPSAFREWRLLGPFRRPTTQLRAKVSSLSHKIRAGGAQRAEAACAQRSEVEAVSLGVPHEVAEGATCQAYELADYSNLRETDI
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P25100 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S18 | Phosphorylation | Uniprot | |
S201 | Phosphorylation | Uniprot | |
S228 | Phosphorylation | Uniprot |
研究背景
This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.
Cell membrane>Multi-pass membrane protein.
Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1D sub-subfamily.
研究领域
· Environmental Information Processing > Signal transduction > Calcium signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
· Organismal Systems > Circulatory system > Adrenergic signaling in cardiomyocytes. (View pathway)
· Organismal Systems > Circulatory system > Vascular smooth muscle contraction. (View pathway)
· Organismal Systems > Digestive system > Salivary secretion.
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