产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9002, RRID:AB_2842198.
展开/折叠
Ha-1; HA1; Hair Keratin acidic hHa1; Hair keratin; hard keratin, type I, 1; hHa1; HKA1; K1H1_HUMAN; K31; keratin 31; Keratin; keratin, hair, acidic,1; keratin, type I cuticular Ha1; Keratin-31; Krt31; KRTHA1; MGC138630; type I cuticular Ha1; type I Ha1; Ha-3I; HA3I; Hair keratin; Hair keratin, type I Ha3-l; Hard keratin, type I,3I; hHa3-I; HHA3-l; HKA3A; K33A; Keratin; Keratin, hair, acidic, 3A; Keratin, type I cuticular Ha3-I; Keratin-33A; Krt1-3; Krt33a; KRTHA3A; KT33A_HUMAN; type I cuticular Ha3-I; type I Ha3-I; HA 3II; HA3II; Hair keratin; Hair keratin type I Ha3 II; Hard keratin type I 3II; hHa3 II; hHa3II; HKA3B; K33B; Keratin 33B; Keratin; Keratin hair acidic 3B; Keratin hair acidic3B; Keratin type I cuticular Ha3 II; Keratin-33B; Keratin33B; KRT 33B; KRT33B; KRTHA 3B; KRTHA3A; KRTHA3B; KT33B_HUMAN; type I cuticular Ha3-II; type I Ha3-II; Type I hair keratin 3B; Ha 4; HA4; Hair keratin; Hair keratin, type I Ha4; Hard keratin type I 4; HHA4; HKA4; K34; Keratin 34; Keratin; Keratin, hair, acidic, 4; Keratin, type I cuticular Ha4; Keratin-34; KRT34; KRT34_HUMAN; KRTHA4; type I cuticular Ha4; type I Ha4;
抗原和靶标
Q15323(K1H1_HUMAN) >>Visit HPA database.
O76009(KT33A_HUMAN) >>Visit HPA database.
Present in scalp but not in hairless skin. Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla.
O76009 KT33A_HUMAN:Expressed in the hair follicles.
O76011 KRT34_HUMAN:Expressed in the hair follicles.
- Q15323 K1H1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPYNFCLPSLSCRTSCSSRPCVPPSCHSCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCNLPSNPCATTNACSKPIGPCLSNPCTSCVPPAPCTPCAPRPRCGPCNSFVR
- O76009 KT33A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSYSCGLPSLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACDKSTGPCISNPCGLRARCGPCNTFGY
- Q14525 KT33B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPYNFCLPSLSCRTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDELTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNETRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACEKPIGSCVTNPCGPRSRCGPCNTFGY
- O76011 KRT34_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLYAKPPPTINGIKGLQRKERLKPAHIHLQQLTCFSITCSSTMSYSCCLPSLGCRTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPSYQSYFKTIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDELTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVLNETRSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPCNPCATTNASGNSCGPCGTSQKGCCN
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q15323/O76009/Q14525/O76011 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
Y70 | Phosphorylation | Uniprot | |
T109 | Phosphorylation | Uniprot | |
Y268 | Phosphorylation | Uniprot | |
T299 | Phosphorylation | Uniprot |
Site | PTM Type | Enzyme | Source |
---|---|---|---|
Y70 | Phosphorylation | Uniprot | |
T109 | Phosphorylation | Uniprot | |
S157 | Phosphorylation | Uniprot | |
Y268 | Phosphorylation | Uniprot |
Site | PTM Type | Enzyme | Source |
---|---|---|---|
Y70 | Phosphorylation | Uniprot | |
S92 | Phosphorylation | Uniprot | |
T109 | Phosphorylation | Uniprot | |
K116 | Acetylation | Uniprot | |
K121 | Acetylation | Uniprot | |
T218 | Phosphorylation | Uniprot | |
Y268 | Phosphorylation | Uniprot | |
T299 | Phosphorylation | Uniprot |
Site | PTM Type | Enzyme | Source |
---|---|---|---|
Y112 | Phosphorylation | Uniprot | |
T151 | Phosphorylation | Uniprot | |
K163 | Ubiquitination | Uniprot | |
S224 | Phosphorylation | Uniprot |
研究背景
Present in scalp but not in hairless skin. Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla.
Belongs to the intermediate filament family.
Expressed in the hair follicles.
Belongs to the intermediate filament family.
Belongs to the intermediate filament family.
Expressed in the hair follicles.
Belongs to the intermediate filament family.
研究领域
· Organismal Systems > Endocrine system > Estrogen signaling pathway. (View pathway)
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