产品: BCL6B 抗体
货号: DF9075
描述: Rabbit polyclonal antibody to BCL6B
应用: WB
反应: Human, Mouse
预测: Pig, Bovine, Horse, Sheep, Dog
分子量: 51 kDa; 52kD(Calculated).
蛋白号: Q8N143
RRID: AB_2842271

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Dog(100%)
克隆:
Polyclonal
特异性:
BCL6B Antibody detects endogenous levels of total BCL6B.
RRID:
AB_2842271
引用格式: Affinity Biosciences Cat# DF9075, RRID:AB_2842271.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

B cell CLL/lymphoma 6, member B (zinc finger protein); B-cell CLL/lymphoma 6, member B (zinc finger protein); BAZF; Bcl6 associated zinc finger protein; Bcl6-associated zinc finger protein; BCL6B; ZBTB28; Zinc finger protein 62; ZNF62;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
Q8N143 BCL6B_HUMAN:

Ubiquitously expressed with higher expression found in heart and placenta.

序列:
MGSPAAPEGALGYVREFTRHSSDVLGNLNELRLRGILTDVTLLVGGQPLRAHKAVLIACSGFFYSIFRGRAGVGVDVLSLPGGPEARGFAPLLDFMYTSRLRLSPATAPAVLAAATYLQMEHVVQACHRFIQASYEPLGISLRPLEAEPPTPPTAPPPGSPRRSEGHPDPPTESRSCSQGPPSPASPDPKACNWKKYKYIVLNSQASQAGSLVGERSSGQPCPQARLPSGDEASSSSSSSSSSSEEGPIPGPQSRLSPTAATVQFKCGAPASTPYLLTSQAQDTSGSPSERARPLPGSEFFSCQNCEAVAGCSSGLDSLVPGDEDKPYKCQLCRSSFRYKGNLASHRTVHTGEKPYHCSICGARFNRPANLKTHSRIHSGEKPYKCETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTRFRHLQTLKSHVRIHTGEKPYHCDPCGLHFRHKSQLRLHLRQKHGAATNTKVHYHILGGP

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Zebrafish
56
Rabbit
50
Xenopus
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q8N143 作为底物

Site PTM Type Enzyme
S3 Phosphorylation
S160 Phosphorylation
T172 Phosphorylation
S174 Phosphorylation
S236 Phosphorylation
S237 Phosphorylation
S238 Phosphorylation
S239 Phosphorylation
S257 Phosphorylation
S379 Phosphorylation

研究背景

功能:

Acts as a sequence-specific transcriptional repressor in association with BCL6. May function in a narrow stage or be related to some events in the early B-cell development.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitously expressed with higher expression found in heart and placenta.

亚基结构:

Associates with BCL6 through the BTB domain.

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