| 产品: | AGPAT7 抗体 |
| 货号: | DF9092 |
| 描述: | Rabbit polyclonal antibody to AGPAT7 |
| 应用: | WB |
| 反应: | Human |
| 预测: | Rabbit |
| 分子量: | 57 kDa; 57kD(Calculated). |
| 蛋白号: | Q643R3 |
| RRID: | AB_2842288 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9092, RRID:AB_2842288.
展开/折叠
1 acyl sn glycerol 3 phosphate acyltransferase eta; 1 AGP acyltransferase 7; 1 AGPAT 7; Acyltransferase like 3; AGPAT7; AYTL3; LPAAT eta; Lpcat4; LPEAT2; Lysophosphatidic acid acyltransferase eta; Lysophosphatidylcholine acyltransferase 4;
抗原和靶标
- Q643R3 LPCT4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSQGSPGDWAPLDPTPGPPASPNPFVHELHLSRLQRVKFCLLGALLAPIRVLLAFIVLFLLWPFAWLQVAGLSEEQLQEPITGWRKTVCHNGVLGLSRLLFFLLGFLRIRVRGQRASRLQAPVLVAAPHSTFFDPIVLLPCDLPKVVSRAENLSVPVIGALLRFNQAILVSRHDPASRRRVVEEVRRRATSGGKWPQVLFFPEGTCSNKKALLKFKPGAFIAGVPVQPVLIRYPNSLDTTSWAWRGPGVLKVLWLTASQPCSIVDVEFLPVYHPSPEESRDPTLYANNVQRVMAQALGIPATECEFVGSLPVIVVGRLKVALEPQLWELGKVLRKAGLSAGYVDAGAEPGRSRMISQEEFARQLQLSDPQTVAGAFGYFQQDTKGLVDFRDVALALAALDGGRSLEELTRLAFELFAEEQAEGPNRLLYKDGFSTILHLLLGSPHPAATALHAELCQAGSSQGLSLCQFQNFSLHDPLYGKLFSTYLRPPHTSRGTSQTPNASSPGNPTALANGTVQAPKQKGD
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q643R3 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| S97 | Phosphorylation | Uniprot | |
| K145 | Ubiquitination | Uniprot | |
| K216 | Ubiquitination | Uniprot | |
| K319 | Ubiquitination | Uniprot | |
| K331 | Ubiquitination | Uniprot | |
| K335 | Ubiquitination | Uniprot | |
| T496 | Phosphorylation | Uniprot | |
| S497 | Phosphorylation | Uniprot | |
| T499 | Phosphorylation | Uniprot | |
| S503 | Phosphorylation | Uniprot |
研究背景
Displays acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates; converts lysophosphatidylethanolamine to phosphatidylethanolamine, lysophosphatidylcholine to phosphatidycholine, 1-alkenyl-lysophatidylethanolamine to 1-alkenyl-phosphatidylethanolamine, lysophosphatidylglycerol and alkyl-lysophosphatidylcholine to phosphatidylglycerol and alkyl-phosphatidylcholine, respectively. In contrast, has no lysophosphatidylinositol, glycerol-3-phosphate, diacylglycerol or lysophosphatidic acid acyltransferase activity. Prefers long chain acyl-CoAs (C16, C18) as acyl donors.
Endoplasmic reticulum membrane>Multi-pass membrane protein.
Widely expressed with predominant level in brain.
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
研究领域
· Metabolism > Lipid metabolism > Glycerophospholipid metabolism.
· Metabolism > Lipid metabolism > Ether lipid metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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