产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9099, RRID:AB_2842295.
展开/折叠
2 acylglycerol O acyltransferase 3; 2-acylglycerol O-acyltransferase 3; Acyl CoA:monoacylglycerol acyltransferase 3; Acyl coenzyme A:monoacylglycerol acyltransferase 3; Acyl-CoA:monoacylglycerol acyltransferase 3; DC 7; DC7; DGAT2L7; Diacylglycerol acyltransferase 2 like protein 7; Diacylglycerol acyltransferase 2-like protein 7; Diacylglycerol O acyltransferase candidate 7; Diacylglycerol O-acyltransferase candidate 7; hDC 7; hDC7; MGAT 3; MGAT3; MGC119203; MGC119204; MOGAT 3; MOGAT3; MOGT3_HUMAN; Monoacylglycerol O acyltransferase 3; Monoacylglycerol O-acyltransferase 3;
抗原和靶标
Selectively expressed in the digestive system. Highly expressed in the ileum, and at lower level in jejunum, duodenum, colon, cecum and the rectum. Not expressed in the stomach and the esophagus and trachea. Expressed at very low level in liver.
- Q86VF5 MOGT3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGVATTLQPPTTSKTLQKQHLEAVGAYQYVLTFLFMGPFFSLLVFVLLFTSLWPFSVFYLVWLYVDWDTPNQGGRRSEWIRNRAIWRQLRDYYPVKLVKTAELPPDRNYVLGAHPHGIMCTGFLCNFSTESNGFSQLFPGLRPWLAVLAGLFYLPVYRDYIMSFGLCPVSRQSLDFILSQPQLGQAVVIMVGGAHEALYSVPGEHCLTLQKRKGFVRLALRHGASLVPVYSFGENDIFRLKAFATGSWQHWCQLTFKKLMGFSPCIFWGRGLFSATSWGLLPFAVPITTVVGRPIPVPQRLHPTEEEVNHYHALYMTALEQLFEEHKESCGVPASTCLTFI
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl-CoA as substrates. Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes.
Ubiquitinated. Ubiquitination leads to proteasomal degradation.
Endoplasmic reticulum membrane>Multi-pass membrane protein. Cytoplasm>Perinuclear region.
Selectively expressed in the digestive system. Highly expressed in the ileum, and at lower level in jejunum, duodenum, colon, cecum and the rectum. Not expressed in the stomach and the esophagus and trachea. Expressed at very low level in liver.
Belongs to the diacylglycerol acyltransferase family.
研究领域
· Metabolism > Lipid metabolism > Glycerolipid metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Digestive system > Fat digestion and absorption.
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