| 产品: | ACOT11 抗体 |
| 货号: | DF9156 |
| 描述: | Rabbit polyclonal antibody to ACOT11 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 68 kDa; 68kD(Calculated). |
| 蛋白号: | Q8WXI4 |
| RRID: | AB_2842352 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9156, RRID:AB_2842352.
展开/折叠
ACO11_HUMAN; ACOT 11; ACOT11; Acyl CoA thioester hydrolase 11; Acyl CoA thioesterase 11; Acyl coenzyme A thioesterase 11; Acyl-CoA thioester hydrolase 11; Acyl-CoA thioesterase 11; Acyl-coenzyme A thioesterase 11; Adipose associated thioesterase; Adipose-associated thioesterase; BFIT 1; BFIT 2; BFIT; BFIT1; BFIT2; Brown fat inducible thioesterase; Brown fat-inducible thioesterase; KIAA0707; OTTHUMP00000046722; StAR related lipid transfer (START) domain containing 14; STARD 14; STARD14; START domain containing 14; THEA; THEM 1; THEM1; Thioesterase adipose associated; Thioesterase superfamily member 1;
抗原和靶标
Isoform 1 is predominantly expressed in skeletal muscle, liver, testis, stomach, spleen, lung and brain. Isoform 2 is predominantly expressed in kidney, uterus, hibernoma and white adipose tissue.
- Q8WXI4 ACO11_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MIQNVGNHLRRGLASVFSNRTSRKSALRAGNDSAMADGEGYRNPTEVQMSQLVLPCHTNQRGELSVGQLLKWIDTTACLSAERHAGCPCVTASMDDIYFEHTISVGQVVNIKAKVNRAFNSSMEVGIQVASEDLCSEKQWNVCKALATFVARREITKVKLKQITPRTEEEKMEHSVAAERRRMRLVYADTIKDLLANCAIQGDLESRDCSRMVPAEKTRVESVELVLPPHANHQGNTFGGQIMAWMENVATIAASRLCRAHPTLKAIEMFHFRGPSQVGDRLVLKAIVNNAFKHSMEVGVCVEAYRQEAETHRRHINSAFMTFVVLDADDQPQLLPWIRPQPGDGERRYREASARKKIRLDRKYIVSCKQTEVPLSVPWDPSNQVYLSYNNVSSLKMLVAKDNWVLSSEISQVRLYTLEDDKFLSFHMEMVVHVDAAQAFLLLSDLRQRPEWDKHYRSVELVQQVDEDDAIYHVTSPALGGHTKPQDFVILASRRKPCDNGDPYVIALRSVTLPTHRETPEYRRGETLCSGFCLWREGDQLTKCCWVRVSLTELVSASGFYSWGLESRSKGRRSDGWNGKLAGGHLSTLKAIPVAKINSRFGYLQDT
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q8WXI4 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T45 | Phosphorylation | Uniprot | |
| S388 | Phosphorylation | Uniprot | |
| S444 | Phosphorylation | Uniprot |
研究背景
Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.
Mitochondrion matrix. Cytoplasm.
Isoform 1 is predominantly expressed in skeletal muscle, liver, testis, stomach, spleen, lung and brain. Isoform 2 is predominantly expressed in kidney, uterus, hibernoma and white adipose tissue.
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