| 产品: | SLC25A5 抗体 |
| 货号: | DF9179 |
| 描述: | Rabbit polyclonal antibody to SLC25A5 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 33 kDa; 33kD(Calculated). |
| 蛋白号: | P05141 |
| RRID: | AB_2842375 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9179, RRID:AB_2842375.
展开/折叠
2F1; AAC2; Adenine nucleotide translocator 2; ADP; ADP ATP carrier protein 2; ADP/ATP translocase 2; ADT2_HUMAN; ANT 2; ANT2; ATP carrier protein 2; ATP carrier protein; fibroblast isoform; OTTHUMP00000024324; SLC25A5; Solute carrier family 25 (mitochondrial carrier adenine nucleotide translocator) member 5; Solute carrier family 25 member 5; T2; T3;
抗原和靶标
- P05141 ADT2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P05141 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| T2 | Acetylation | Uniprot | |
| T2 | Phosphorylation | Uniprot | |
| S7 | Phosphorylation | Uniprot | |
| K10 | Acetylation | Uniprot | |
| K10 | Methylation | Uniprot | |
| K10 | Ubiquitination | Uniprot | |
| S22 | Phosphorylation | Uniprot | |
| K23 | Acetylation | Uniprot | |
| K23 | Ubiquitination | Uniprot | |
| T24 | Phosphorylation | Uniprot | |
| K33 | Acetylation | Uniprot | |
| K33 | Ubiquitination | Uniprot | |
| S42 | Phosphorylation | Uniprot | |
| K43 | Acetylation | Uniprot | |
| K43 | Methylation | Uniprot | |
| K43 | Ubiquitination | Uniprot | |
| K49 | Ubiquitination | Uniprot | |
| K52 | Acetylation | Uniprot | |
| K52 | Methylation | Uniprot | |
| K52 | Ubiquitination | Uniprot | |
| K63 | Acetylation | Uniprot | |
| K63 | Ubiquitination | Uniprot | |
| S69 | Phosphorylation | Uniprot | |
| Y81 | Phosphorylation | Uniprot | |
| T84 | Phosphorylation | Uniprot | |
| K92 | Acetylation | Uniprot | |
| K92 | Ubiquitination | Uniprot | |
| K94 | Acetylation | Uniprot | |
| K96 | Acetylation | Uniprot | |
| K96 | Ubiquitination | Uniprot | |
| K105 | Acetylation | Uniprot | |
| K105 | Ubiquitination | Uniprot | |
| Y112 | Phosphorylation | Uniprot | |
| S119 | Phosphorylation | Uniprot | |
| C129 | S-Nitrosylation | Uniprot | |
| T139 | Phosphorylation | Uniprot | |
| R140 | Methylation | Uniprot | |
| K147 | Methylation | Uniprot | |
| K147 | Ubiquitination | Uniprot | |
| R155 | Methylation | Uniprot | |
| C160 | S-Nitrosylation | Uniprot | |
| K163 | Acetylation | Uniprot | |
| K163 | Ubiquitination | Uniprot | |
| K166 | Methylation | Uniprot | |
| K166 | Ubiquitination | Uniprot | |
| S167 | Phosphorylation | Uniprot | |
| Y191 | Phosphorylation | Uniprot | |
| Y195 | Phosphorylation | Uniprot | |
| T197 | Phosphorylation | Uniprot | |
| K199 | Acetylation | Uniprot | |
| K199 | Sumoylation | Uniprot | |
| K199 | Ubiquitination | Uniprot | |
| K206 | Sumoylation | Uniprot | |
| S242 | Phosphorylation | Uniprot | |
| K245 | Ubiquitination | Uniprot | |
| T247 | Phosphorylation | Uniprot | |
| T252 | Phosphorylation | Uniprot | |
| T254 | Phosphorylation | Uniprot | |
| C257 | S-Nitrosylation | Uniprot | |
| K268 | Acetylation | Uniprot | |
| K268 | Ubiquitination | Uniprot | |
| K272 | Acetylation | Uniprot | |
| K272 | Methylation | Uniprot | |
| K272 | Ubiquitination | Uniprot | |
| S276 | Phosphorylation | Uniprot | |
| K295 | Acetylation | Uniprot | |
| K295 | Ubiquitination | Uniprot | |
| Y297 | Phosphorylation | Uniprot |
研究背景
Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.
Trimethylated by ANTKMT at Lys-52.
Mitochondrion inner membrane>Multi-pass membrane protein.
Homodimer. Component of the MMXD complex, which includes CIAO1, ERCC2, CIAO2B, MMS19 and SLC25A5. Interacts with AK4.
(Microbial infection) Interacts with HIV-1 Vpr.
The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. Odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue.
Belongs to the mitochondrial carrier (TC 2.A.29) family.
研究领域
· Cellular Processes > Cell growth and death > Necroptosis. (View pathway)
· Cellular Processes > Cell growth and death > Cellular senescence. (View pathway)
· Environmental Information Processing > Signal transduction > Calcium signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway. (View pathway)
· Human Diseases > Neurodegenerative diseases > Parkinson's disease.
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
· Human Diseases > Infectious diseases: Viral > HTLV-I infection.
限制条款
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