| 产品: | ABCA5 抗体 |
| 货号: | DF9246 |
| 描述: | Rabbit polyclonal antibody to ABCA5 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Horse, Rabbit |
| 分子量: | 187kDa; 187kD(Calculated). |
| 蛋白号: | Q8WWZ7 |
| RRID: | AB_2842442 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9246, RRID:AB_2842442.
展开/折叠
ABC13; ABCA5; ABCA5_HUMAN; ATP binding cassette sub family A (ABC1) member 5; ATP binding cassette A5; ATP binding cassette sub family A member 5; ATP-binding cassette sub-family A member 5; DKFZp451F117; DKFZp779N2435; EST90625; FLJ16381; KIAA1888;
抗原和靶标
Ubiquitously expressed. Highly expressed in testis, skeletal muscle, kidney, liver and placenta.
- Q8WWZ7 ABCA5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSTAIREVGVWRQTRTLLLKNYLIKCRTKKSSVQEILFPLFFLFWLILISMMHPNKKYEEVPNIELNPMDKFTLSNLILGYTPVTNITSSIMQKVSTDHLPDVIITEEYTNEKEMLTSSLSKPSNFVGVVFKDSMSYELRFFPDMIPVSSIYMDSRAGCSKSCEAAQYWSSGFTVLQASIDAAIIQLKTNVSLWKELESTKAVIMGETAVVEIDTFPRGVILIYLVIAFSPFGYFLAIHIVAEKEKKIKEFLKIMGLHDTAFWLSWVLLYTSLIFLMSLLMAVIATASLLFPQSSSIVIFLLFFLYGLSSVFFALMLTPLFKKSKHVGIVEFFVTVAFGFIGLMIILIESFPKSLVWLFSPFCHCTFVIGIAQVMHLEDFNEGASFSNLTAGPYPLIITIIMLTLNSIFYVLLAVYLDQVIPGEFGLRRSSLYFLKPSYWSKSKRNYEELSEGNVNGNISFSEIIEPVSSEFVGKEAIRISGIQKTYRKKGENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQLDIHFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQTIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGSSMFLKSKWGIGYRLSMYIDKYCATESLSSLVKQHIPGATLLQQNDQQLVYSLPFKDMDKFSGLFSALDSHSNLGVISYGVSMTTLEDVFLKLEVEAEIDQADYSVFTQQPLEEEMDSKSFDEMEQSLLILSETKAALVSTMSLWKQQMYTIAKFHFFTLKRESKSVRSVLLLLLIFFTVQIFMFLVHHSFKNAVVPIKLVPDLYFLKPGDKPHKYKTSLLLQNSADSDISDLISFFTSQNIMVTMINDSDYVSVAPHSAALNVMHSEKDYVFAAVFNSTMVYSLPILVNIISNYYLYHLNVTETIQIWSTPFFQEITDIVFKIELYFQAALLGIIVTAMPPYFAMENAENHKIKAYTQLKLSGLLPSAYWIGQAVVDIPLFFIILILMLGSLLAFHYGLYFYTVKFLAVVFCLIGYVPSVILFTYIASFTFKKILNTKEFWSFIYSVAALACIAITEITFFMGYTIATILHYAFCIIIPIYPLLGCLISFIKISWKNVRKNVDTYNPWDRLSVAVISPYLQCVLWIFLLQYYEKKYGGRSIRKDPFFRNLSTKSKNRKLPEPPDNEDEDEDVKAERLKVKELMGCQCCEEKPSIMVSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIENLEVDRLQREIQYIFPNASRQESFSSILAYKIPKEDVQSLSQSFFKLEEAKHAFAIEEYSFSQATLEQVFVELTKEQEEEDNSCGTLNSTLWWERTQEDRVVF
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q8WWZ7 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S134 | Phosphorylation | Uniprot | |
| Y137 | Phosphorylation | Uniprot | |
| S155 | Phosphorylation | Uniprot | |
| S192 | Phosphorylation | Uniprot | |
| R218 | Methylation | Uniprot | |
| K490 | Ubiquitination | Uniprot | |
| K608 | Ubiquitination | Uniprot | |
| K614 | Acetylation | Uniprot | |
| S616 | Phosphorylation | Uniprot | |
| K620 | Acetylation | Uniprot | |
| S624 | Phosphorylation | Uniprot | |
| T642 | Phosphorylation | Uniprot | |
| S649 | Phosphorylation | Uniprot | |
| K683 | Methylation | Uniprot | |
| S687 | Phosphorylation | Uniprot | |
| K701 | Ubiquitination | Uniprot | |
| K703 | Ubiquitination | Uniprot | |
| T854 | Phosphorylation | Uniprot | |
| S859 | Phosphorylation | Uniprot | |
| K1050 | Ubiquitination | Uniprot | |
| K1254 | Ubiquitination | Uniprot | |
| Y1299 | Phosphorylation | Uniprot | |
| S1405 | Phosphorylation | Uniprot | |
| S1407 | Phosphorylation | Uniprot | |
| K1410 | Ubiquitination | Uniprot | |
| K1423 | Ubiquitination | Uniprot | |
| K1428 | Ubiquitination | Uniprot | |
| S1562 | Phosphorylation | Uniprot | |
| S1564 | Phosphorylation | Uniprot | |
| S1565 | Phosphorylation | Uniprot | |
| Y1569 | Phosphorylation | Uniprot | |
| K1585 | Ubiquitination | Uniprot |
研究背景
May play a role in the processing of autolysosomes.
N-glycosylated.
Lysosome membrane>Multi-pass membrane protein. Late endosome membrane>Multi-pass membrane protein. Golgi apparatus membrane>Multi-pass membrane protein.
Ubiquitously expressed. Highly expressed in testis, skeletal muscle, kidney, liver and placenta.
Belongs to the ABC transporter superfamily. ABCA family.
研究领域
· Environmental Information Processing > Membrane transport > ABC transporters.
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