ABCA5 Antibody - #DF9246

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产品: ABCA5 抗体
货号: DF9246
描述: Rabbit polyclonal antibody to ABCA5
应用: WB
反应: Human, Mouse, Rat
预测: Horse, Rabbit
分子量: 187kDa; 187kD(Calculated).
蛋白号: Q8WWZ7
RRID: AB_2842442

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Horse(100%), Rabbit(100%)
克隆:
Polyclonal
特异性:
ABCA5 Antibody detects endogenous levels of total ABCA5.
RRID:
AB_2842442
引用格式: Affinity Biosciences Cat# DF9246, RRID:AB_2842442.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

ABC13; ABCA5; ABCA5_HUMAN; ATP binding cassette sub family A (ABC1) member 5; ATP binding cassette A5; ATP binding cassette sub family A member 5; ATP-binding cassette sub-family A member 5; DKFZp451F117; DKFZp779N2435; EST90625; FLJ16381; KIAA1888;

抗原和靶标

免疫原:
Uniprot:

Q8WWZ7(ABCA5_HUMAN) >>Visit HPA database.

基因/基因ID:
ABCA5(23461)
表达:
Q8WWZ7 ABCA5_HUMAN:

Ubiquitously expressed. Highly expressed in testis, skeletal muscle, kidney, liver and placenta.

序列:
MSTAIREVGVWRQTRTLLLKNYLIKCRTKKSSVQEILFPLFFLFWLILISMMHPNKKYEEVPNIELNPMDKFTLSNLILGYTPVTNITSSIMQKVSTDHLPDVIITEEYTNEKEMLTSSLSKPSNFVGVVFKDSMSYELRFFPDMIPVSSIYMDSRAGCSKSCEAAQYWSSGFTVLQASIDAAIIQLKTNVSLWKELESTKAVIMGETAVVEIDTFPRGVILIYLVIAFSPFGYFLAIHIVAEKEKKIKEFLKIMGLHDTAFWLSWVLLYTSLIFLMSLLMAVIATASLLFPQSSSIVIFLLFFLYGLSSVFFALMLTPLFKKSKHVGIVEFFVTVAFGFIGLMIILIESFPKSLVWLFSPFCHCTFVIGIAQVMHLEDFNEGASFSNLTAGPYPLIITIIMLTLNSIFYVLLAVYLDQVIPGEFGLRRSSLYFLKPSYWSKSKRNYEELSEGNVNGNISFSEIIEPVSSEFVGKEAIRISGIQKTYRKKGENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQLDIHFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQTIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGSSMFLKSKWGIGYRLSMYIDKYCATESLSSLVKQHIPGATLLQQNDQQLVYSLPFKDMDKFSGLFSALDSHSNLGVISYGVSMTTLEDVFLKLEVEAEIDQADYSVFTQQPLEEEMDSKSFDEMEQSLLILSETKAALVSTMSLWKQQMYTIAKFHFFTLKRESKSVRSVLLLLLIFFTVQIFMFLVHHSFKNAVVPIKLVPDLYFLKPGDKPHKYKTSLLLQNSADSDISDLISFFTSQNIMVTMINDSDYVSVAPHSAALNVMHSEKDYVFAAVFNSTMVYSLPILVNIISNYYLYHLNVTETIQIWSTPFFQEITDIVFKIELYFQAALLGIIVTAMPPYFAMENAENHKIKAYTQLKLSGLLPSAYWIGQAVVDIPLFFIILILMLGSLLAFHYGLYFYTVKFLAVVFCLIGYVPSVILFTYIASFTFKKILNTKEFWSFIYSVAALACIAITEITFFMGYTIATILHYAFCIIIPIYPLLGCLISFIKISWKNVRKNVDTYNPWDRLSVAVISPYLQCVLWIFLLQYYEKKYGGRSIRKDPFFRNLSTKSKNRKLPEPPDNEDEDEDVKAERLKVKELMGCQCCEEKPSIMVSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIENLEVDRLQREIQYIFPNASRQESFSSILAYKIPKEDVQSLSQSFFKLEEAKHAFAIEEYSFSQATLEQVFVELTKEQEEEDNSCGTLNSTLWWERTQEDRVVF

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Rabbit
100
Horse
100
Pig
78
Bovine
67
Sheep
67
Zebrafish
63
Dog
0
Xenopus
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q8WWZ7 作为底物

Site PTM Type Enzyme
S134 Phosphorylation
Y137 Phosphorylation
S155 Phosphorylation
S192 Phosphorylation
R218 Methylation
K490 Ubiquitination
K608 Ubiquitination
K614 Acetylation
S616 Phosphorylation
K620 Acetylation
S624 Phosphorylation
T642 Phosphorylation
S649 Phosphorylation
K683 Methylation
S687 Phosphorylation
K701 Ubiquitination
K703 Ubiquitination
T854 Phosphorylation
S859 Phosphorylation
K1050 Ubiquitination
K1254 Ubiquitination
Y1299 Phosphorylation
S1405 Phosphorylation
S1407 Phosphorylation
K1410 Ubiquitination
K1423 Ubiquitination
K1428 Ubiquitination
S1562 Phosphorylation
S1564 Phosphorylation
S1565 Phosphorylation
Y1569 Phosphorylation
K1585 Ubiquitination

研究背景

功能:

May play a role in the processing of autolysosomes.

翻译修饰:

N-glycosylated.

细胞定位:

Lysosome membrane>Multi-pass membrane protein. Late endosome membrane>Multi-pass membrane protein. Golgi apparatus membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitously expressed. Highly expressed in testis, skeletal muscle, kidney, liver and placenta.

蛋白家族:

Belongs to the ABC transporter superfamily. ABCA family.

研究领域

· Environmental Information Processing > Membrane transport > ABC transporters.

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