| 产品: | KCNJ14 抗体 |
| 货号: | DF9261 |
| 描述: | Rabbit polyclonal antibody to KCNJ14 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat, Monkey |
| 分子量: | 48 kDa; 48kD(Calculated). |
| 蛋白号: | Q9UNX9 |
| RRID: | AB_2842457 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9261, RRID:AB_2842457.
展开/折叠
ATP-sensitive inward rectifier potassium channel 14; Inward rectifier K(+) channel Kir2.4; inwardly rectifying subfamily J member 14; IRK-4; IRK4; KCJ14_HUMAN; Kcnj14; KIR2.4; Potassium channel; Potassium channel inwardly rectifying subfamily J member 14; Potassium inwardly rectifying channel, subfamily J member 14; Potassium voltage gated channel subfamily J member 14;
抗原和靶标
- Q9UNX9 KCJ14_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGLARALRRLSGALDSGDSRAGDEEEAGPGLCRNGWAPAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAFWLIASLHGDLAAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDEDDETEEGNGVETEDGAASPRVLTPTLALTLPP
研究背景
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ14 gives rise to low-conductance channels with a low affinity to the channel blockers Barium and Cesium (By similarity).
Membrane>Multi-pass membrane protein.
Expressed preferentially in retina.
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ14 subfamily.
研究领域
· Organismal Systems > Nervous system > Cholinergic synapse.
· Organismal Systems > Endocrine system > Oxytocin signaling pathway.
限制条款
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