产品: KCNJ15 抗体
货号: DF9262
描述: Rabbit polyclonal antibody to KCNJ15
应用: WB IHC
反应: Human
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
分子量: 43 kDa; 43kD(Calculated).
蛋白号: Q99712
RRID: AB_2842458

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
IHC 1:50-1:200, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
预测:
Pig(94%), Bovine(94%), Horse(94%), Sheep(94%), Rabbit(94%), Dog(94%), Chicken(94%)
克隆:
Polyclonal
特异性:
KCNJ15 Antibody detects endogenous levels of total KCNJ15.
RRID:
AB_2842458
引用格式: Affinity Biosciences Cat# DF9262, RRID:AB_2842458.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

ATP sensitive inward rectifier potassium channel 15; ATP-sensitive inward rectifier potassium channel 15; Inward rectifier K(+) channel Kir1.3; Inward rectifier K(+) channel Kir4.2; Inward rectifier K+ channel KIR4.2; inwardly rectifying subfamily J member 15; IRK15_HUMAN; IRKK; KCNJ 14; KCNJ 15; KCNJ14; Kcnj15; KIR1.3; KIR4.2; MGC13584; Potassium channel; Potassium channel inwardly rectifying subfamily J member 15; Potassium inwardly rectifying channel J15; Potassium inwardly rectifying channel subfamily J member 15;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
序列:
MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQRERELRTLLLQQSNV

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Pig
94
Horse
94
Bovine
94
Sheep
94
Dog
94
Chicken
94
Rabbit
94
Zebrafish
67
Xenopus
53
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q99712 作为底物

Site PTM Type Enzyme
K348 Ubiquitination

研究背景

功能:

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

细胞定位:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Interacts with PATJ.

蛋白家族:

Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ15 subfamily.

研究领域

· Organismal Systems > Digestive system > Gastric acid secretion.

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