GCNT4 Antibody - #DF9268

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产品: GCNT4 抗体
货号: DF9268
描述: Rabbit polyclonal antibody to GCNT4
应用: WB
反应: Human, Mouse
预测: Pig, Bovine, Horse, Sheep, Dog
分子量: 53kDa; 53kD(Calculated).
蛋白号: Q9P109
RRID: AB_2842464

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
预测:
Pig(82%), Bovine(82%), Horse(91%), Sheep(82%), Dog(82%)
克隆:
Polyclonal
特异性:
GCNT4 Antibody detects endogenous levels of total GCNT4.
RRID:
AB_2842464
引用格式: Affinity Biosciences Cat# DF9268, RRID:AB_2842464.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Core 2 (beta-1,6-N-acetylglucosaminyltransferase); Core 2 branching enzyme 3; Core2 GlcNAc transferase 3; GCNT4; Glucosaminyl (N-acetyl) transferase 4;

抗原和靶标

免疫原:
Uniprot:

Q9P109(GCNT4_HUMAN) >>Visit HPA database.

基因/基因ID:
GCNT4(51301)
表达:
Q9P109 GCNT4_HUMAN:

Predominantly expressed in thymus. Weakly expressed in pancreas, peripheral blood leukocytes, placenta, small intestine and stomach. Barely detectable in liver, spleen, lung and lymph node.

序列:
MKIFKCYFKHTLQQKVFILFLTLWLLSLLKLLNVRRLFPQKDIYLVEYSLSTSPFVRNRYTHVKDEVRYEVNCSGIYEQEPLEIGKSLEIRRRDIIDLEDDDVVAMTSDCDIYQTLRGYAQKLVSKEEKSFPIAYSLVVHKDAIMVERLIHAIYNQHNIYCIHYDRKAPDTFKVAMNNLAKCFSNIFIASKLEAVEYAHISRLQADLNCLSDLLKSSIQWKYVINLCGQDFPLKSNFELVSELKKLNGANMLETVKPPNSKLERFTYHHELRRVPYEYVKLPIRTNISKEAPPHNIQIFVGSAYFVLSQAFVKYIFNNSIVQDFFAWSKDTYSPDEHFWATLIRVPGIPGEISRSAQDVSDLQSKTRLVKWNYYEGFFYPSCTGSHLRSVCIYGAAELRWLIKDGHWFANKFDSKVDPILIKCLAEKLEEQQRDWITLPSEKLFMDRNLTTTS

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Horse
91
Pig
82
Bovine
82
Sheep
82
Dog
82
Rabbit
73
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q9P109 作为底物

Site PTM Type Enzyme
K41 Acetylation
Y48 Phosphorylation
Y60 Phosphorylation
Y135 Phosphorylation
Y379 Phosphorylation
S381 Phosphorylation
T383 Phosphorylation
S385 Phosphorylation

研究背景

功能:

Glycosyltransferase that mediates core 2 O-glycan branching, an important step in mucin-type biosynthesis. Does not have core 4 O-glycan or I-branching enzyme activity.

细胞定位:

Golgi apparatus membrane>Single-pass type II membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Predominantly expressed in thymus. Weakly expressed in pancreas, peripheral blood leukocytes, placenta, small intestine and stomach. Barely detectable in liver, spleen, lung and lymph node.

蛋白家族:

Belongs to the glycosyltransferase 14 family.

研究领域

· Metabolism > Glycan biosynthesis and metabolism > Mucin type O-glycan biosynthesis.

· Metabolism > Global and overview maps > Metabolic pathways.

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