| 产品: | CHST11 抗体 |
| 货号: | DF9327 |
| 描述: | Rabbit polyclonal antibody to CHST11 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 42 kDa; 42kD(Calculated). |
| 蛋白号: | Q9NPF2 |
| RRID: | AB_2842523 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9327, RRID:AB_2842523.
展开/折叠
C4S-1; C4ST 1; C4ST; C4ST-1; C4ST1; Carbohydrate (chondroitin 4) sulfotransferase 11; Carbohydrate sulfotransferase 11; Chondroitin 4 O sulfotransferase 1; Chondroitin 4 sulfotransferase; Chondroitin 4-O-sulfotransferase 1; Chondroitin 4-sulfotransferase 1; CHST 11; Chst11; CHSTB_HUMAN; HSA269537; IgH/CHST11 fusion;
抗原和靶标
Widely expressed. Highly expressed in spleen, thymus, bone marrow, peripheral blood leukocytes, lymph node, heart, brain, lung and placenta.
- Q9NPF2 CHSTB_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSMLHPVMRRNPFGVDICCRKGSRSPLQELYNPIQLELSNTAVLHQMRRDQVTDTCRANSATSRKRRVLTPNDLKHLVVDEDHELIYCYVPKVACTNWKRLMMVLTGRGKYSDPMEIPANEAHVSANLKTLNQYSIPEINHRLKSYMKFLFVREPFERLVSAYRNKFTQKYNISFHKRYGTKIIKRQRKNATQEALRKGDDVKFEEFVAYLIDPHTQREEPFNEHWQTVYSLCHPCHIHYDLVGKYETLEEDSNYVLQLAGVGSYLKFPTYAKSTRTTDEMTTEFFQNISSEHQTQLYEVYKLDFLMFNYSVPSYLKLE
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9NPF2 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K2 | Ubiquitination | Uniprot | |
| K143 | Ubiquitination | Uniprot | |
| K162 | Ubiquitination | Uniprot | |
| K210 | Ubiquitination | Uniprot | |
| N342 | N-Glycosylation | Uniprot |
研究背景
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.
N-glycosylated; required for activity and stability.
Golgi apparatus membrane>Single-pass type II membrane protein.
Widely expressed. Highly expressed in spleen, thymus, bone marrow, peripheral blood leukocytes, lymph node, heart, brain, lung and placenta.
Belongs to the sulfotransferase 2 family.
研究领域
· Metabolism > Glycan biosynthesis and metabolism > Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate.
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