产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9337, RRID:AB_2842533.
展开/折叠
Carboxypeptidase A6; Carboxypeptidase B; CBPA6_HUMAN; CPA6; CPAH;
抗原和靶标
- Q8N4T0 CBPA6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKCLGKRRGQAAAFLPLCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKISYQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLKKCP
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q8N4T0 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S60 | Phosphorylation | Uniprot | |
T216 | Phosphorylation | Uniprot | |
Y326 | Phosphorylation | Uniprot | |
Y334 | Phosphorylation | Uniprot | |
Y336 | Phosphorylation | Uniprot | |
Y368 | Phosphorylation | Uniprot | |
Y376 | Phosphorylation | Uniprot | |
Y387 | Phosphorylation | Uniprot |
研究背景
May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II. Releases a C-terminal amino acid, with preference for large hydrophobic C-terminal amino acids and shows only very weak activity toward small amino acids and histidine.
Secreted>Extracellular space>Extracellular matrix.
Expressed in the hippocampus, nucleus raphe, and cortex.
Belongs to the peptidase M14 family.
限制条款
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