| 产品: | CHSY3 抗体 |
| 货号: | DF9378 |
| 描述: | Rabbit polyclonal antibody to CHSY3 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Bovine, Dog |
| 分子量: | 100 kDa; 100kD(Calculated). |
| 蛋白号: | Q70JA7 |
| RRID: | AB_2842574 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9378, RRID:AB_2842574.
展开/折叠
Carbohydrate synthase 2; Chondroitin glucuronyltransferase 3; Chondroitin sulfate synthase 3; Chondroitin synthase 2; CHSS3_HUMAN; ChSy-2; CHSY2; Chsy3; CSS3; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3; N-acetylgalactosaminyltransferase 3;
抗原和靶标
- Q70JA7 CHSS3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAVRSRRPWMSVALGLVLGFTAASWLIAPRVAELSERKRRGSSLCSYYGRSAAGPRAGAQQPLPQPQSRPRQEQSPPPARQDLQGPPLPEAAPGITSFRSSPWQQPPPLQQRRRGREPEGATGLPGAPAAEGEPEEEDGGAAGQRRDGRPGSSHNGSGDGGAAAPSARPRDFLYVGVMTAQKYLGSRALAAQRTWARFIPGRVEFFSSQQPPNAGQPPPPLPVIALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDVYIKGDKLEEFLRSLNSSKPLYLGQTGLGNIEELGKLGLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWSYEMQQLFHENYEHNRKGYIQDLHNSKIHAAITLHPNKRPAYQYRLHNYMLSRKISELRYRTIQLHRESALMSKLSNTEVSKEDQQLGVIPSFNHFQPRERNEVIEWEFLTGKLLYSAAENQPPRQSLSSILRTALDDTVLQVMEMINENAKSRGRLIDFKEIQYGYRRVNPMHGVEYILDLLLLYKRHKGRKLTVPVRRHAYLQQLFSKPFFRETEELDVNSLVESINSETQSFSFISNSLKILSSFQGAKEMGGHNEKKVHILVPLIGRYDIFLRFMENFENMCLIPKQNVKLVIILFSRDSGQDSSKHIELIKGYQNKYPKAEMTLIPMKGEFSRGLGLEMASAQFDNDTLLLFCDVDLIFREDFLQRCRDNTIQGQQVYYPIIFSQYDPKVTNGGNPPTDDYFIFSKKTGFWRDYGYGITCIYKSDLLGAGGFDTSIQGWGLEDVDLYNKVILSGLRPFRSQEVGVVHIFHPVHCDPNLDPKQYKMCLGSKASTFASTMQLAELWLEKHLGVRYNRTLS
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q70JA7 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T96 | Phosphorylation | Uniprot | |
| S97 | Phosphorylation | Uniprot | |
| S100 | O-Glycosylation | Uniprot | |
| S101 | O-Glycosylation | Uniprot | |
| S411 | Phosphorylation | Uniprot | |
| Y526 | Phosphorylation | Uniprot | |
| T687 | Phosphorylation | Uniprot | |
| S860 | Phosphorylation | Uniprot |
研究背景
Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity is much reduced compared to CHSY1.
Golgi apparatus>Golgi stack membrane>Single-pass type II membrane protein.
Detected at low levels in brain, cerebral cortex, uterus and small intestine.
Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
研究领域
· Metabolism > Glycan biosynthesis and metabolism > Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate.
· Metabolism > Global and overview maps > Metabolic pathways.
限制条款
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