| 产品: | Claudin 14 抗体 |
| 货号: | DF9391 |
| 描述: | Rabbit polyclonal antibody to Claudin 14 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Rabbit, Dog, Chicken |
| 分子量: | 26 kDa; 26kD(Calculated). |
| 蛋白号: | O95500 |
| RRID: | AB_2842587 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9391, RRID:AB_2842587.
展开/折叠
AI851731; Claudin 14; Claudin-14; CLD14_HUMAN; CLDN 14; CLDN14; DFNB 29; DFNB29; Human CLDN14 gene; MGC109472; OTTHUMP00000109046; OTTHUMP00000109049; OTTMUSP00000021531; UNQ777/PRO1571;
抗原和靶标
- O95500 CLD14_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O95500 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y194 | Phosphorylation | Uniprot | |
| Y211 | Phosphorylation | Uniprot | |
| Y217 | Phosphorylation | Uniprot | |
| Y233 | Phosphorylation | Uniprot |
研究背景
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Cell junction>Tight junction. Cell membrane>Multi-pass membrane protein.
Liver, kidney. Also found in ear.
Belongs to the claudin family.
研究领域
· Cellular Processes > Cellular community - eukaryotes > Tight junction. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > Cell adhesion molecules (CAMs). (View pathway)
· Human Diseases > Infectious diseases: Viral > Hepatitis C.
· Organismal Systems > Immune system > Leukocyte transendothelial migration. (View pathway)
限制条款
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