NT5C2 Antibody - #DF9431

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产品: NT5C2 抗体
货号: DF9431
描述: Rabbit polyclonal antibody to NT5C2
应用: WB IHC
反应: Human, Mouse, Monkey
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 65 kDa; 65kD(Calculated).
蛋白号: P49902
RRID: AB_2842627

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Monkey
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
克隆:
Polyclonal
特异性:
NT5C2 Antibody detects endogenous levels of total NT5C2.
RRID:
AB_2842627
引用格式: Affinity Biosciences Cat# DF9431, RRID:AB_2842627.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

5' nucleotidase (purine) cytosolic type B; 5NTC_HUMAN; cN II; Cytosolic 5''-nucleotidase II; Cytosolic IMP/GMP-specific 5'-nucleotidase; Cytosolic purine 5' nucleotidase; Cytosolic purine 5''-nucleotidase; GMP; NT5B; nt5c2; NT5CP; NUCLEOTIDASE, 5-PRIME, CYTOSOLIC II; NUCLEOTIDASE, 5-PRIME, TYPE B; PNT5; PURINE 5-PRIME-NUCLEOTIDASE;

抗原和靶标

免疫原:
Uniprot:

P49902(5NTC_HUMAN) >>Visit HPA database.

基因/基因ID:
NT5C2(22978)
序列:
MSTSWSDRLQNAADMPANMDKHALKKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLSFAYDSTFPTRGLVFDTLYGNLLKVDAYGNLLVCAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLACLVDFFTNCPRYTSCETGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPLLLSRMKEVGKVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPLFFGEGTVLRQVDTKTGKLKIGTYTGPLQHGIVYSGGSSDTICDLLGAKGKDILYIGDHIFGDILKSKKRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQRRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAAHVLMPHESTVEHTHVDINEMESPLATRNRTSVDFKDTDYKRHQLTRSISEIKPPNLFPLAPQEITHCHDEDDDEEEEEEEE

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Chicken
100
Rabbit
100
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P49902 作为底物

Site PTM Type Enzyme
T3 Phosphorylation
S4 Phosphorylation
K21 Ubiquitination
K26 Acetylation
Y32 Phosphorylation
K140 Ubiquitination
Y178 Phosphorylation
K186 Ubiquitination
S193 Phosphorylation
K211 Ubiquitination
K217 Ubiquitination
K224 Ubiquitination
K228 Ubiquitination
K231 Ubiquitination
S237 Phosphorylation
K244 Ubiquitination
K254 Ubiquitination
K292 Ubiquitination
K313 Ubiquitination
K342 Ubiquitination
K344 Ubiquitination
K359 Ubiquitination
S410 Phosphorylation
S418 Phosphorylation
T427 Phosphorylation
S439 Phosphorylation
S502 Phosphorylation
T510 Phosphorylation
S511 Phosphorylation
K515 Ubiquitination
Y519 Phosphorylation
K520 Ubiquitination
S527 Phosphorylation
S529 Phosphorylation
K532 Ubiquitination

研究背景

功能:

May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.

细胞定位:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Homotetramer.

蛋白家族:

Belongs to the 5'(3')-deoxyribonucleotidase family.

研究领域

· Metabolism > Nucleotide metabolism > Purine metabolism.

· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.

· Metabolism > Metabolism of cofactors and vitamins > Nicotinate and nicotinamide metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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