| 产品: | RPAB3 抗体 |
| 货号: | DF9466 |
| 描述: | Rabbit polyclonal antibody to RPAB3 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Chicken, Xenopus |
| 分子量: | 17,23 kDa; 17kD(Calculated). |
| 蛋白号: | P52434 |
| RRID: | AB_2842662 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9466, RRID:AB_2842662.
展开/折叠
and III 17.1 kDa polypeptide; and III subunit ABC3; DNA directed RNA polymerases I, II, and III 17.1 kDa polypeptide; DNA directed RNA polymerases I, II, and III subunit RPABC3; DNA-directed RNA polymerase II subunit H; DNA-directed RNA polymerases I; DNA-directed RNA polymerases I, II, and III subunit RPABC3; hRPB8; HsRPB8; II; POLR2H; Polymerase (RNA) II (DNA directed) polypeptide H; RNA polymerases I; RNA polymerases I, II, and III subunit ABC3; RPAB3_HUMAN; RPABC3; RPB17; RPB8; RPB8 homolog;
抗原和靶标
- P52434 RPAB3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAGILFEDIFDVKDIDPEGKKFDRVSRLHCESESFKMDLILDVNIQIYPVDLGDKFRLVIASTLYEDGTLDDGEYNPTDDRPSRADQFEYVMYGKVYRIEGDETSTEAATRLSAYVSYGGLLMRLQGDANNLHGFEVDSRVYLLMKKLAF
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P52434 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| K13 | Ubiquitination | Uniprot | |
| K20 | Ubiquitination | Uniprot | |
| K21 | Ubiquitination | Uniprot | |
| Y65 | Phosphorylation | Uniprot | |
| Y75 | Phosphorylation | Uniprot | |
| T78 | Phosphorylation | Uniprot | |
| Y90 | Phosphorylation | Uniprot | |
| K95 | Ubiquitination | Uniprot | |
| T104 | Phosphorylation | Uniprot | |
| Y118 | Phosphorylation | Uniprot | |
| Y142 | Phosphorylation | Uniprot | |
| K146 | Ubiquitination | Uniprot | |
| K147 | Ubiquitination | Uniprot |
研究背景
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
Nucleus>Nucleolus.
Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively. Directly interacts with POLR2A.
Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
研究领域
· Genetic Information Processing > Transcription > RNA polymerase.
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
· Human Diseases > Infectious diseases: Viral > Epstein-Barr virus infection.
· Metabolism > Nucleotide metabolism > Purine metabolism.
· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Immune system > Cytosolic DNA-sensing pathway. (View pathway)
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