| 产品: | ELOVL2 抗体 |
| 货号: | DF9495 |
| 描述: | Rabbit polyclonal antibody to ELOVL2 |
| 应用: | WB |
| 反应: | Human |
| 预测: | Zebrafish, Horse, Rabbit, Dog, Xenopus |
| 分子量: | 35 kDa; 35kD(Calculated). |
| 蛋白号: | Q9NXB9 |
| RRID: | AB_2842691 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9495, RRID:AB_2842691.
展开/折叠
3 keto acyl CoA synthase ELOVL2; 3-keto acyl-CoA synthase Elovl2; Elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast) like 2; Elongation of very long chain fatty acids protein 2; ELOV2_HUMAN; ELOVL fatty acid elongase 2; Elovl2; FLJ20334; OTTHUMP00000016029; SSC2;
抗原和靶标
- Q9NXB9 ELOV2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEHLKAFDDEINAFLDNMFGPRDSRVRGWFMLDSYLPTFFLTVMYLLSIWLGNKYMKNRPALSLRGILTLYNLGITLLSAYMLAELILSTWEGGYNLQCQDLTSAGEADIRVAKVLWWYYFSKSVEFLDTIFFVLRKKTSQITFLHVYHHASMFNIWWCVLNWIPCGQSFFGPTLNSFIHILMYSYYGLSVFPSMHKYLWWKKYLTQAQLVQFVLTITHTMSAVVKPCGFPFGCLIFQSSYMLTLVILFLNFYVQTYRKKPMKKDMQEPPAGKEVKNGFSKAYFTAANGVMNKKAQ
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9NXB9 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K293 | Acetylation | Uniprot |
研究背景
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Endoplasmic reticulum membrane>Multi-pass membrane protein.
Liver and testis.
The C-terminal di-lysine motif may confer endoplasmic reticulum localization.
Belongs to the ELO family. ELOVL2 subfamily.
研究领域
· Metabolism > Lipid metabolism > Fatty acid elongation.
· Metabolism > Lipid metabolism > Biosynthesis of unsaturated fatty acids.
· Metabolism > Global and overview maps > Fatty acid metabolism.
限制条款
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