| 产品: | GNB3 抗体 |
| 货号: | DF9565 |
| 描述: | Rabbit polyclonal antibody to GNB3 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Rabbit, Dog, Xenopus |
| 分子量: | 37 kDa; 37kD(Calculated). |
| 蛋白号: | P16520 |
| RRID: | AB_2842761 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9565, RRID:AB_2842761.
展开/折叠
G protein beta 3 subunit; GBB3_HUMAN; GNB3; GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3; GTP binding regulatory protein beta 3 chain; Guanine nucleotide binding protein (G protein) beta polypeptide 3; Guanine nucleotide binding protein G; Guanine nucleotide binding protein G(I)/G(S)/G(T) beta subunit 3; Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Hypertension associated protein; IG; SG; Transducin beta chain 3; Tsubunit beta 3;
抗原和靶标
- P16520 GBB3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGEMEQLRQEAEQLKKQIADARKACADVTLAELVSGLEVVGRVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P16520 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y59 | Phosphorylation | Uniprot | |
| S72 | Phosphorylation | Uniprot | |
| S74 | Phosphorylation | Uniprot | |
| K78 | Acetylation | Uniprot | |
| Y85 | Phosphorylation | Uniprot | |
| T86 | Phosphorylation | Uniprot | |
| T87 | Phosphorylation | Uniprot | |
| S140 | Phosphorylation | Uniprot | |
| T143 | Phosphorylation | Uniprot | |
| Y145 | Phosphorylation | Uniprot | |
| K177 | Ubiquitination | Uniprot | |
| S309 | Phosphorylation | Uniprot |
研究背景
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
G proteins are composed of 3 units, alpha, beta and gamma. Interacts with RASD2.
Belongs to the WD repeat G protein beta family.
研究领域
· Environmental Information Processing > Signal transduction > Ras signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Apelin signaling pathway. (View pathway)
· Human Diseases > Substance dependence > Morphine addiction.
· Human Diseases > Substance dependence > Alcoholism.
· Human Diseases > Cancers: Overview > Pathways in cancer. (View pathway)
· Organismal Systems > Immune system > Chemokine signaling pathway. (View pathway)
· Organismal Systems > Environmental adaptation > Circadian entrainment.
· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling. (View pathway)
· Organismal Systems > Nervous system > Glutamatergic synapse.
· Organismal Systems > Nervous system > Cholinergic synapse.
· Organismal Systems > Nervous system > Serotonergic synapse.
· Organismal Systems > Nervous system > GABAergic synapse.
· Organismal Systems > Nervous system > Dopaminergic synapse.
· Organismal Systems > Sensory system > Taste transduction.
· Organismal Systems > Endocrine system > Relaxin signaling pathway.
限制条款
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