| 产品: | KIR2DS5 抗体 |
| 货号: | DF9601 |
| 描述: | Rabbit polyclonal antibody to KIR2DS5 |
| 应用: | WB IF/ICC |
| 反应: | Human |
| 分子量: | 34 kDa; 34kD(Calculated). |
| 蛋白号: | Q14953 |
| RRID: | AB_2842797 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9601, RRID:AB_2842797.
展开/折叠
CD158 antigen like family member G; CD158g; Flags: Precursor; Killer cell immunoglobulin like receptor 2DS5; Killer cell immunoglobulin like receptor two domains short cytoplasmic tail 5; KIR2DS5; MHC class I NK cell receptor; Natural killer associated transcript 9; Natural killer cell inhibitory receptor; NKAT 9; NKAT9;
抗原和靶标
- Q14953 KI2S5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLMVISMACVAFFLLQGAWPHEGFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGTFNHTLRLIGEHIDGVSKGNFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRTFQADFPLDPATHGGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNSSNSWPSPTEPSSETGNPRHLHVLIGTSVVKLPFTILLFFLLHRWCSNKKNASVMDQGPAGNRTVNREDSDEQDHQEVSYA
翻译修饰 - Q14953 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N178 | N-Glycosylation | Uniprot |
研究背景
Activating natural killer (NK) receptor that recognizes C2 epitopes of HLA-C alleles. Bridging the innate and adaptive immune systems, NK cells express a number of cell surface receptors which either inhibit or stimulate their cytotoxicity. Able to activate NK cells citotoxicity and cytokine production such as IFNG. Receptor functions are attenuated even lost in some alleles, such as KIR2DS5*002 reprensented in this entry.
N-glycosylated, glycosylation varies depending on the allele which alters cell surface expression levels.
Cell membrane>Single-pass type I membrane protein>Extracellular side.
Expressed on a discrete subset of peripheral blood NK cells.
Interacts with TYROBP.
Belongs to the immunoglobulin superfamily.
研究领域
· Organismal Systems > Immune system > Antigen processing and presentation. (View pathway)
· Organismal Systems > Immune system > Natural killer cell mediated cytotoxicity. (View pathway)
限制条款
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