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| 产品: | NDUFA1 抗体 |
| 货号: | DF9659 |
| 描述: | Rabbit polyclonal antibody to NDUFA1 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Chicken, Xenopus |
| 分子量: | 8 kDa; 8kD(Calculated). |
| 蛋白号: | O15239 |
| RRID: | AB_2842855 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9659, RRID:AB_2842855.
展开/折叠
CI MWFE; CI-MWFE; Complex I MWFE; complex I MWFE subunit; Complex I-MWFE; MWFE; MWFE, B. taurus, homolog of; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1 7.5kDa; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1; NADH oxidoreductase subunit MWFE; NADH ubiquinone oxidoreductase (complex 1); NADH ubiquinone oxidoreductase MWFE subunit; NADH-ubiquinone oxidoreductase 1 alpha subcomplex, 1; NADH-ubiquinone oxidoreductase MWFE subunit; NDUA1_HUMAN; NDUFA 1; NDUFA1; Type I dehydrogenase; ZNF 183; ZNF183;
抗原和靶标
- O15239 NDUA1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MWFEILPGLSVMGVCLLIPGLATAYIHRFTNGGKEKRVAHFGYHWSLMERDRRISGVDRYYVSKGLENID
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O15239 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S55 | Phosphorylation | Uniprot | |
| R59 | Methylation | Uniprot | |
| Y60 | Phosphorylation | Uniprot | |
| Y61 | Phosphorylation | Uniprot | |
| S63 | Phosphorylation | Uniprot | |
| K64 | Ubiquitination | Uniprot |
研究背景
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Mitochondrion inner membrane>Single-pass membrane protein>Matrix side.
Primarily expressed in heart and skeletal muscle.
Complex I is composed of 45 different subunits.
Belongs to the complex I NDUFA1 subunit family.
研究领域
· Human Diseases > Endocrine and metabolic diseases > Non-alcoholic fatty liver disease (NAFLD).
· Human Diseases > Neurodegenerative diseases > Alzheimer's disease.
· Human Diseases > Neurodegenerative diseases > Parkinson's disease.
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
· Metabolism > Energy metabolism > Oxidative phosphorylation.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling. (View pathway)
文献引用
Application: WB Species: human Sample: Liver
限制条款
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