| 产品: | NDUFA5 抗体 |
| 货号: | DF9660 |
| 描述: | Rabbit polyclonal antibody to NDUFA5 |
| 应用: | WB |
| 反应: | Human, Mouse |
| 预测: | Pig, Zebrafish, Bovine, Dog |
| 分子量: | 13 kDa; 13kD(Calculated). |
| 蛋白号: | Q16718 |
| RRID: | AB_2842856 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9660, RRID:AB_2842856.
展开/折叠
B13; CI 13kB; CI-13kD-B; Complex I subunit B13; Complex I-13kD-B; DKFZp781K1356; FLJ12147; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (13kD, B13); NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5; NADH-ubiquinone oxidoreductase 13 kDa-B subunit; NDUA5_HUMAN; NDUFA5; NUFM; Type I dehydrogenase; Ubiquinone reductase; UQOR13;
抗原和靶标
Expressed in all tissues examined with highest levels in heart, skeletal muscle and brain.
- Q16718 NDUA5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAGVLKKTTGLVGLAVCNTPHERLRILYTKILDVLEEIPKNAAYRKYTEQITNEKLAMVKAEPDVKKLEDQLQGGQLEEVILQAEHELNLARKMREWKLWEPLVEEPPADQWKWPI
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q16718 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| C17 | S-Nitrosylation | Uniprot | |
| Y28 | Phosphorylation | Uniprot | |
| K30 | Acetylation | Uniprot | |
| K60 | Acetylation | Uniprot | |
| K60 | Sumoylation | Uniprot |
研究背景
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Mitochondrion inner membrane>Peripheral membrane protein>Matrix side.
Expressed in all tissues examined with highest levels in heart, skeletal muscle and brain.
Complex I is composed of 45 different subunits.
Belongs to the complex I NDUFA5 subunit family.
研究领域
· Human Diseases > Endocrine and metabolic diseases > Non-alcoholic fatty liver disease (NAFLD).
· Human Diseases > Neurodegenerative diseases > Alzheimer's disease.
· Human Diseases > Neurodegenerative diseases > Parkinson's disease.
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
· Metabolism > Energy metabolism > Oxidative phosphorylation.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling. (View pathway)
限制条款
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