| 产品: | NUP133 抗体 |
| 货号: | DF9706 |
| 描述: | Rabbit polyclonal antibody to NUP133 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 129 kDa; 129kD(Calculated). |
| 蛋白号: | Q8WUM0 |
| RRID: | AB_2842901 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9706, RRID:AB_2842901.
展开/折叠
133 kDa nucleoporin; FLJ10814; hNUP 133; hNUP133; MGC21133; NU133_HUMAN; Nuclear pore complex protein Nup133; Nucleoporin 133kDa; Nucleoporin NUP133; NUP 133; NUP133; OTTHUMP00000061095;
抗原和靶标
- Q8WUM0 NU133_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MFPAAPSPRTPGTGSRRGPLAGLGPGSTPRTASRKGLPLGSAVSSPVLFSPVGRRSSLSSRGTPTRMFPHHSITESVNYDVKTFGSSLPVKVMEALTLAEVDDQLTINIDEGGWACLVCKEKLIIWKIALSPITKLSVCKELQLPPSDFHWSADLVALSYSSPSGEAHSTQAVAVMVATREGSIRYWPSLAGEDTYTEAFVDSGGDKTYSFLTAVQGGSFILSSSGSQLIRLIPESSGKIHQHILPQGQGMLSGIGRKVSSLFGILSPSSDLTLSSVLWDRERSSFYSLTSSNISKWELDDSSEKHAYSWDINRALKENITDAIWGSESNYEAIKEGVNIRYLDLKQNCDGLVILAAAWHSADNPCLIYYSLITIEDNGCQMSDAVTVEVTQYNPPFQSEDLILCQLTVPNFSNQTAYLYNESAVYVCSTGTGKFSLPQEKIVFNAQGDSVLGAGACGGVPIIFSRNSGLVSITSRENVSILAEDLEGSLASSVAGPNSESMIFETTTKNETIAQEDKIKLLKAAFLQYCRKDLGHAQMVVDELFSSHSDLDSDSELDRAVTQISVDLMDDYPASDPRWAESVPEEAPGFSNTSLIILHQLEDKMKAHSFLMDFIHQVGLFGRLGSFPVRGTPMATRLLLCEHAEKLSAAIVLKNHHSRLSDLVNTAILIALNKREYEIPSNLTPADVFFREVSQVDTICECLLEHEEQVLRDAPMDSIEWAEVVINVNNILKDMLQAASHYRQNRNSLYRREESLEKEPEYVPWTATSGPGGIRTVIIRQHEIVLKVAYPQADSNLRNIVTEQLVALIDCFLDGYVSQLKSVDKSSNRERYDNLEMEYLQKRSDLLSPLLSLGQYLWAASLAEKYCDFDILVQMCEQTDNQSRLQRYMTQFADQNFSDFLFRWYLEKGKRGKLLSQPISQHGQLANFLQAHEHLSWLHEINSQELEKAHATLLGLANMETRYFAKKKTLLGLSKLAALASDFSEDMLQEKIEEMAEQERFLLHQETLPEQLLAEKQLNLSAMPVLTAPQLIGLYICEENRRANEYDFKKALDLLEYIDEEEDININDLKLEILCKALQRDNWSSSDGKDDPIEVSKDSIFVKILQKLLKDGIQLSEYLPEVKDLLQADQLGSLKSNPYFEFVLKANYEYYVQGQI
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q8WUM0 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| S7 | Phosphorylation | Uniprot | |
| R9 | Methylation | Uniprot | |
| T10 | Phosphorylation | Uniprot | |
| T13 | Phosphorylation | Uniprot | |
| S15 | Phosphorylation | Uniprot | |
| R17 | Methylation | Uniprot | |
| S27 | Phosphorylation | P24941 (CDK2) | Uniprot |
| T28 | Phosphorylation | P24941 (CDK2) | Uniprot |
| T31 | Phosphorylation | Uniprot | |
| S33 | Phosphorylation | Uniprot | |
| K35 | Ubiquitination | Uniprot | |
| S41 | Phosphorylation | Uniprot | |
| S44 | Phosphorylation | Uniprot | |
| S45 | Phosphorylation | Uniprot | |
| S50 | Phosphorylation | P24941 (CDK2) | Uniprot |
| S56 | Phosphorylation | Uniprot | |
| S57 | Phosphorylation | Uniprot | |
| S59 | Phosphorylation | Uniprot | |
| S60 | Phosphorylation | Uniprot | |
| R61 | Methylation | Uniprot | |
| T63 | Phosphorylation | Uniprot | |
| T65 | Phosphorylation | Uniprot | |
| S72 | Phosphorylation | Uniprot | |
| T74 | Phosphorylation | Uniprot | |
| S76 | Phosphorylation | Uniprot | |
| K82 | Sumoylation | Uniprot | |
| K82 | Ubiquitination | Uniprot | |
| S131 | Phosphorylation | Uniprot | |
| T134 | Phosphorylation | Uniprot | |
| K135 | Ubiquitination | Uniprot | |
| T197 | Phosphorylation | Uniprot | |
| T213 | Phosphorylation | Uniprot | |
| S223 | Phosphorylation | Uniprot | |
| K239 | Ubiquitination | Uniprot | |
| K258 | Ubiquitination | Uniprot | |
| S260 | Phosphorylation | Uniprot | |
| S261 | Phosphorylation | Uniprot | |
| S267 | Phosphorylation | Uniprot | |
| K296 | Ubiquitination | Uniprot | |
| S303 | Phosphorylation | Uniprot | |
| K305 | Ubiquitination | Uniprot | |
| K317 | Ubiquitination | Uniprot | |
| K335 | Ubiquitination | Uniprot | |
| S450 | Phosphorylation | Uniprot | |
| S480 | Phosphorylation | Uniprot | |
| S489 | Phosphorylation | Uniprot | |
| S499 | Phosphorylation | Uniprot | |
| T512 | Phosphorylation | Uniprot | |
| K518 | Ubiquitination | Uniprot | |
| K523 | Ubiquitination | Uniprot | |
| S546 | Phosphorylation | Uniprot | |
| S547 | Phosphorylation | Uniprot | |
| S549 | Phosphorylation | Uniprot | |
| S553 | Phosphorylation | Uniprot | |
| S582 | Phosphorylation | Uniprot | |
| K674 | Ubiquitination | Uniprot | |
| S681 | Phosphorylation | Uniprot | |
| S755 | Phosphorylation | Uniprot | |
| K758 | Acetylation | Uniprot | |
| K758 | Ubiquitination | Uniprot | |
| Y762 | Phosphorylation | Uniprot | |
| K787 | Ubiquitination | Uniprot | |
| Y832 | Phosphorylation | Uniprot | |
| K842 | Ubiquitination | Uniprot | |
| K913 | Ubiquitination | Uniprot | |
| T961 | Phosphorylation | Uniprot | |
| K967 | Ubiquitination | Uniprot | |
| K968 | Ubiquitination | Uniprot | |
| T969 | Phosphorylation | Uniprot | |
| S981 | Phosphorylation | Uniprot | |
| K991 | Ubiquitination | Uniprot | |
| S1021 | Phosphorylation | Uniprot | |
| T1027 | Phosphorylation | Uniprot | |
| Y1046 | Phosphorylation | Uniprot | |
| K1049 | Ubiquitination | Uniprot | |
| K1076 | Ubiquitination | Uniprot | |
| S1084 | Phosphorylation | Uniprot | |
| S1085 | Phosphorylation | Uniprot | |
| S1086 | Phosphorylation | Uniprot | |
| K1089 | Ubiquitination | Uniprot | |
| K1097 | Ubiquitination | Uniprot | |
| K1107 | Ubiquitination | Uniprot | |
| K1110 | Ubiquitination | Uniprot | |
| K1123 | Ubiquitination | Uniprot | |
| S1133 | Phosphorylation | Uniprot | |
| K1135 | Ubiquitination | Uniprot | |
| Y1150 | Phosphorylation | Uniprot |
研究背景
Involved in poly(A)+ RNA transport. Involved in nephrogenesis.
Nucleus>Nuclear pore complex. Chromosome>Centromere>Kinetochore.
Note: Located on both the cytoplasmic and nuclear sides of the nuclear pore (PubMed:11564755). During mitosis, localizes to the kinetochores (PubMed:11564755).
Widely expressed in fetal and adult tissues. Expressed in the brain and kidney.
Forms part of the Nup160 subcomplex in the nuclear pore which is composed of NUP160, NUP133, NUP107 and Nup96. This complex plays a role in RNA export and in tethering Nup98 and NUP153 to the nucleus.
Belongs to the nucleoporin Nup133 family.
研究领域
· Genetic Information Processing > Translation > RNA transport.
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