| 产品: | NUP205 抗体 |
| 货号: | DF9709 |
| 描述: | Rabbit polyclonal antibody to NUP205 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 228 kDa; 228kD(Calculated). |
| 蛋白号: | Q92621 |
| RRID: | AB_2842904 |
产品描述
来源:
Rabbit
应用:
IHC 1:50-1:200, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
反应:
Human,Mouse,Rat
预测:
Pig(88%), Bovine(88%), Horse(88%), Sheep(88%), Rabbit(88%), Dog(100%), Chicken(88%), Xenopus(88%)
克隆:
Polyclonal
特异性:
NUP205 Antibody detects endogenous levels of total NUP205.
RRID:
AB_2842904
引用格式: Affinity Biosciences Cat# DF9709, RRID:AB_2842904.
引用格式: Affinity Biosciences Cat# DF9709, RRID:AB_2842904.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:
展开/折叠
205 kDa nucleoporin; C7orf14; KIAA0225; NU205_HUMAN; Nuclear pore complex protein Nup205; Nucleoporin Nup205; NUP205;
抗原和靶标
免疫原:
Uniprot:
基因/基因ID:
序列:
- Q92621 NU205_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATPLAVNSAASLWGPYKDIWHKVGNALWRRQPEAVHLLDKILKKHKPDFISLFKNPPKNVQQHEKVQKASTEGVAIQGQQGTRLLPEQLIKEAFILSDLFDIGELAAVELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCIANSLKALIQSRRGKTWTLELSPELASMTTRFTDELMEQGLTYKVLTLVSQIDVNNEFEKLQRERGLGSEKHRKEVSDLIKECRQSLAESLFAWACQSPLGKEDTLLLIGHLERVTVEANGSLDAVNLALLMALLYCFDISFIEQSTEERDDMIHQLPLLTEKQYIATIHSRLQDSQLWKLPGLQATVRLAWALALRGISQLPDVTALAEFTEADEAMAELAIADNVFLFLMESVVVSEYFYQEEFYIRRVHNLITDFLALMPMKVKQLRNRADEDARMIHMSMQMGNEPPISLRRDLEHLMLLIGELYKKNPFHLELALEYWCPTEPLQTPTIMGSYLGVAHQRPPQRQVVLSKFVRQMGDLLPPTIYIPYLKMLQGLANGPQCAHYCFSLLKVNGSSHVENIQGAGGSPVSWEHFFHSLMLYHEHLRKDLPSADSVQYRHLPSRGITQKEQDGLIAFLQLTSTIITWSENARLALCEHPQWTPVVVILGLLQCSIPPVLKAELLKTLAAFGKSPEIAASLWQSLEYTQILQTVRIPSQRQAIGIEVELNEIESRCEEYPLTRAFCQLISTLVESSFPSNLGAGLRPPGFDPYLQFLRDSVFLRFRTRAYRRAAEKWEVAEVVLEVFYKLLRDYEPQLEDFVDQFVELQGEEIIAYKPPGFSLMYHLLNESPMLELALSLLEEGVKQLDTYAPFPGKKHLEKAVQHCLALLNLTLQKENLFMDLLRESQLALIVCPLEQLLQGINPRTKKADNVVNIARYLYHGNTNPELAFESAKILCCISCNSNIQIKLVGDFTHDQSISQKLMAGFVECLDCEDAEEFVRLEEGSELEKKLVAIRHETRIHILNLLITSLECNPPNLALYLLGFELKKPVSTTNLQDPGVLGCPRTCLHAILNILEKGTEGRTGPVAVRESPQLAELCYQVIYQLCACSDTSGPTMRYLRTSQDFLFSQLQYLPFSNKEYEISMLNQMSWLMKTASIELRVTSLNRQRSHTQRLLHLLLDDMPVKPYSDGEGGIEDENRSVSGFLHFDTATKVRRKILNILDSIDFSQEIPEPLQLDFFDRAQIEQVIANCEHKNLRGQTVCNVKLLHRVLVAEVNALQGMAAIGQRPLLMEEISTVLQYVVGRNKLLQCLHAKRHALESWRQLVEIILTACPQDLIQAEDRQLIIRDILQDVHDKILDDEAAQELMPVVAGAVFTLTAHLSQAVLTEQKETSVLGPAEAHYAFMLDSCFTSPPPEENPLVGFASIGDSSLYIILKKLLDFILKTGGGFQRVRTHLYGSLLYYLQIAQRPDEPDTLEAAKKTMWERLTAPEDVFSKLQRENIAIIESYGAALMEVVCRDACDGHEIGRMLALALLDRIVSVDKQQQWLLYLSNSGYLKVLVDSLVEDDRTLQSLLTPQPPLLKALYTYESKMAFLTRVAKIQQGALELLRSGVIVRLAQCQVYDMRPETDPQSMFGMRDPPMFIPTPVDRYRQILLPALQLCQVILTSSMAQHLQAAGQVLQFLISHSDTIQAILRCQDVSAGSLQELALLTGIISKAALPGILSELDVDVNEGSLMELQGHIGRFQRQCLGLLSRFGGSDRLRQFKFQDDNVEGDKVSKKDEIELAMQQICANVMEYCQSLMLQSSPTFQHAVCLFTPSLSETVNRDGPRQDTQAPVVPYWRLPGLGIIIYLLKQSANDFFSYYDSHRQSVSKLQNVEQLPPDEIKELCQSVMPAGVDKISTAQKYVLARRRLVKVINNRAKLLSLCSFIIETCLFILWRHLEYYLLHCMPTDSQDSLFASRTLFKSRRLQDSFASETNLDFRSGLAIVSQHDLDQLQADAINAFGESLQKKLLDIEGLYSKVRSRYSFIQALVRRIRGLLRISRN
种属预测
种属预测:
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
Species
Results
Score
Dog
100
Pig
88
Horse
88
Bovine
88
Sheep
88
Xenopus
88
Chicken
88
Rabbit
88
Zebrafish
67
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q92621 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| T3 | Phosphorylation | Uniprot | |
| K18 | Ubiquitination | Uniprot | |
| K23 | Ubiquitination | Uniprot | |
| K41 | Ubiquitination | Uniprot | |
| K55 | Ubiquitination | Uniprot | |
| K66 | Ubiquitination | Uniprot | |
| K69 | Ubiquitination | Uniprot | |
| T72 | Phosphorylation | Uniprot | |
| K139 | Sumoylation | Uniprot | |
| K147 | Sumoylation | Uniprot | |
| K147 | Ubiquitination | Uniprot | |
| K156 | Ubiquitination | Uniprot | |
| K201 | Ubiquitination | Uniprot | |
| K215 | Ubiquitination | Uniprot | |
| S218 | Phosphorylation | Uniprot | |
| K222 | Ubiquitination | Uniprot | |
| K304 | Ubiquitination | Uniprot | |
| K321 | Ubiquitination | Uniprot | |
| T328 | Phosphorylation | Uniprot | |
| S434 | Phosphorylation | Uniprot | |
| Y450 | Phosphorylation | Uniprot | |
| K451 | Ubiquitination | Uniprot | |
| K496 | Ubiquitination | Uniprot | |
| K571 | Ubiquitination | Uniprot | |
| S575 | Phosphorylation | Uniprot | |
| Y581 | Phosphorylation | Uniprot | |
| K648 | Ubiquitination | Uniprot | |
| T649 | Phosphorylation | Uniprot | |
| K655 | Ubiquitination | Uniprot | |
| Y833 | Phosphorylation | Uniprot | |
| T890 | Phosphorylation | Uniprot | |
| K892 | Ubiquitination | Uniprot | |
| Y902 | Phosphorylation | Uniprot | |
| Y904 | Phosphorylation | Uniprot | |
| T908 | Phosphorylation | Uniprot | |
| K918 | Ubiquitination | Uniprot | |
| S942 | Phosphorylation | Uniprot | |
| S970 | Phosphorylation | Uniprot | |
| K1013 | Ubiquitination | Uniprot | |
| K1042 | Ubiquitination | Uniprot | |
| K1150 | Ubiquitination | Uniprot | |
| Y1152 | Phosphorylation | Uniprot | |
| S1153 | Phosphorylation | Uniprot | |
| S1165 | Phosphorylation | Uniprot | |
| S1167 | Phosphorylation | Uniprot | |
| K1177 | Ubiquitination | Uniprot | |
| K1219 | Ubiquitination | Uniprot | |
| T1225 | Phosphorylation | Uniprot | |
| K1230 | Ubiquitination | Uniprot | |
| K1271 | Ubiquitination | Uniprot | |
| K1279 | Ubiquitination | Uniprot | |
| K1446 | Ubiquitination | Uniprot | |
| K1461 | Ubiquitination | Uniprot | |
| S1505 | Phosphorylation | Uniprot | |
| K1548 | Ubiquitination | Uniprot | |
| K1565 | Ubiquitination | Uniprot | |
| S1666 | Phosphorylation | Uniprot | |
| K1732 | Ubiquitination | Uniprot | |
| K1742 | Ubiquitination | Uniprot | |
| T1799 | Phosphorylation | Uniprot | |
| K1839 | Ubiquitination | Uniprot | |
| K1865 | Ubiquitination | Uniprot | |
| T1868 | Phosphorylation | Uniprot | |
| K1871 | Ubiquitination | Uniprot | |
| K1881 | Ubiquitination | Uniprot | |
| K1932 | Methylation | Uniprot | |
| S1939 | Phosphorylation | Uniprot | |
| S1942 | Phosphorylation | Uniprot | |
| T1944 | Phosphorylation | Uniprot | |
| K1977 | Ubiquitination | Uniprot | |
| K1978 | Ubiquitination | Uniprot | |
| Y1986 | Phosphorylation | Uniprot | |
| K1988 | Ubiquitination | Uniprot |
研究背景
功能:
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor NUP62 and other nucleoporins, but not NUP153 and TPR, to the NPC.
细胞定位:
Nucleus membrane>Peripheral membrane protein. Nucleus>Nuclear pore complex.
Note: Localized near the center, on both the cytoplasmic and nuclear side, of the NPC core structure.
亚基结构:
Part of the nuclear pore complex (NPC). Forms a complex with NUP35, NUP93, NUP155 and lamin B. Does not interact with TPR.
蛋白家族:
Belongs to the NUP186/NUP192/NUP205 family.
研究领域
· Genetic Information Processing > Translation > RNA transport.
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